42041-50-9Relevant articles and documents
Facile dearomatizing radical arylation of furan and thiophene
Crich, David,Patel, Mitesh
, p. 3625 - 3628 (2005)
(Chemical Equation Presented) In the presence of catalytic diphenyl diselenide, reduced in situ to benzeneselenol, tributyltin hydride and V-70 promote the addition of aryl iodides to furan and thiophene. The adduct radicals are trapped by the selenol to give the 2-aryl-2,3-dihydro and 2-aryl-2,5-dihydro heterocyclic products. When the iodide is an o-iodophenol, a cyclization follows the radical addition and provides bridged bicyclic acetals.
C–H Arylation of N-Heteroarenes under Metal-Free Conditions and its Application towards the Synthesis of Pentabromo- and Pentachloropseudilins
Kumar, Mukesh,Sharma, Shweta,Sil, Parijat,Kushwaha, Manoj,Mayor, Satyajit,Vishwakarma, Ram A.,Singh, Parvinder Pal
, p. 3591 - 3598 (2019/06/20)
Herein, we are reporting metal-free conditions for radical initiation and direct C–H arylation of N-heteroarenes. Starting from aniline, the corresponding arenediazonium salt generated in situ is reduced to an aryl radical in the presence of chloropromazine hydrochloride, a new reagent for this application. The optimized procedures are mild, operationally simple, and are working successfully with more diverse substrates in comparison to reported methods. The optimized method is also employed for the synthesis of marine natural products Pentabromo- and Pentachloropseudilins (PBP/PCP). In the present study, we also validated the potential of the Pentachloropseudilin (PCP), thus synthesized, for inhibition of Myosin1 function in mammalian cells and confirmed that PCP phenocopies Myosin1c depletion in cells.
Circularly Polarized Luminescence from Helically Chiral N,N,O,O-Boron-Chelated Dipyrromethenes
Alnoman, Rua B.,Rihn, Sandra,O'Connor, Daniel C.,Black, Fiona A.,Costello, Bernard,Waddell, Paul G.,Clegg, William,Peacock, Robert D.,Herrebout, Wouter,Knight, Julian G.,Hall, Michael J.
, p. 93 - 96 (2016/01/25)
Helically chiral N,N,O,O-boron chelated dipyrromethenes showed solution-phase circularly polarized luminescence (CPL) in the red region of the visible spectrum (λem(max) from 621 to 663 nm). The parent dipyrromethene is desymmetrised through O
Synthesis of pentabromopseudilin and other arylpyrrole derivatives via Heck arylations
Schwalm, Cristiane S.,De Castro, Ilton B.D.,Ferrari, Jailton,De Oliveira, Fábio L.,Aparicio, Ricardo,Correia, Carlos Roque D.
, p. 1660 - 1663 (2012/04/10)
Pentrabromopseudilin and other 2 and 3-arylpyrrole derivatives were synthesized through the Heck-Matsuda reaction involving endocyclic enecarbamates and N-protected 3-pyrrolines, respectively. The overall processes permitted an easy and efficient access t
