42052-51-7Relevant articles and documents
Novel use of cross-linked poly(N-isopropylacrylamide) gel for organic reactions in aqueous media
Hamamoto, Hiromi,Kudoh, Masahiro,Takahashi, Hideyo,Ikegami, Shiro
, p. 4015 - 4018 (2006)
A poly(N-isopropylacrylamide) (PNIPAAm) gel cross-linked with quaternized aminoalkyls was designed. A novel recyclable system based on the external solvent-responsive oil-absorption/elution transition ability of the PNIPAAm gel matrix was then developed.
Selective Cα-O Bond Cleavage of α,β-Epoxy Ketones to Aldols induced by Free Radical Processes
Hasegawa, Eietsu,Ishiyama, Kenyuki,Horaguchi, Takaaki,Shimizu, Takahachi
, p. 550 - 552 (1990)
Several α,β-epoxy ketones were converted to aldols in good yields upon irradiation or heating with azoisobutyronitrile in the presence of tributyltin hydride in benzene; the reactions involve selective Cα-O bond cleavage of the oxiranylmethyl r
Cellulosic CuI Nanoparticles as a Heterogeneous, Recyclable Catalyst for the Borylation of α,β-Unsaturated Acceptors in Aqueous Media
Zhou, Lijie,Han, Biao,Zhang, Yaoyao,Li, Bojie,Wang, Liansheng,Wang, Jianying,Wang, Xianbao,Zhu, Lei
, p. 3220 - 3229 (2021/03/06)
Abstract: We have demonstrated that cellulosic CuI nanoparticles could perform as an efficient heterogeneous catalyst for the synthesis of useful organoboron compounds. Desired β-borylation products were all obtained in good to excellent yields under mild
All at once arrangement of both oxygen atoms of dioxygen into aliphatic C(sp3)-C(sp3) bonds for hydroxyketone difunctionalization
Qiao, Xiaofeng,Lin, Yuhan,Li, Jiazhen,Ma, Wanhong,Zhao, Jincai
, p. 770 - 777 (2021/04/09)
Both β- and γ- hydroxyketone structures are important units in biologically active molecules, synthetic drugs and fine chemicals. Although there are some routes available for their manufacture from pre-functionalized groups on one or two matrix molecule(s), the approaches to simply and simultaneously deposit two oxygen atoms from dioxygen into two specific C(sp3) positions of pure saturated hydrocarbons have rarely succeeded because they are involved in the targeted activation of three inert C-H σ bonds all at once. Here, we show that a TiO2-CH3CN photocatalytic suspension system enables the insertion of dioxygen into one C(sp3)-C(sp3) bond of strained cycloparaffin derivatives, by which difunctionalized hydroxyketone products are obtained in a one-pot reaction. With the cleavage event to release strain as the directional driving force, as-designed photocatalytic reaction systems show 21 examples of β-hydroxyketone products with 31%–76% isolated yields for three-membered ring derivatives and 5 examples of γ-hydroxyketone products with 30%–63% isolated yields for four-membered ring substrates. 18O isotopic labeling experiments using 18O2, Ti18O2 and intentionally added H218O, respectively, indicated that both oxygen atoms of hydroxyketone products were exclusively from dioxygen, suggesting a previously unknown H+/TiO2-e? catalyzed arrangement pathway of the hydroperoxide intermediate to convert dioxygen into hydroxyketone units. [Figure not available: see fulltext.]
