42115-48-0 Usage
Description
2-Bromobutyric acid n-butyl ester is an organic compound characterized by the molecular formula C8H15BrO2. It is a colorless liquid with a slightly fruity odor and is widely recognized as a chemical intermediate.
Used in Pharmaceutical Industry:
2-Bromobutyric acid n-butyl ester is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromobutyric acid n-butyl ester serves as an essential component in the production of agrochemicals, aiding in the creation of more effective and targeted pest control solutions.
Used in Organic Compound Synthesis:
2-Bromobutyric acid n-butyl ester is utilized as a versatile building block in the synthesis of other organic compounds, broadening its applications across different chemical domains.
Used as a Solvent or Reagent:
2-BROMOBUTYRIC ACID N-BUTYL ESTER also functions as a solvent or reagent in various chemical reactions, facilitating processes and enhancing the yield of desired products.
Safety Precautions:
Check Digit Verification of cas no
The CAS Registry Mumber 42115-48-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,1,1 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 42115-48:
(7*4)+(6*2)+(5*1)+(4*1)+(3*5)+(2*4)+(1*8)=80
80 % 10 = 0
So 42115-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H15BrO2/c1-3-5-6-11-8(10)7(9)4-2/h7H,3-6H2,1-2H3
42115-48-0Relevant articles and documents
Novel ibuprofen prodrugs with improved pharmacokinetics and non-ulcerogenic potential
Dhakane, Valmik D.,Chavan, Hemant V.,Thakare, Vishnu N.,Adsul, Laxman K.,Shringare, Sadanand N.,Bandgar, Babasaheb P.
, p. 503 - 517 (2014/03/21)
In the present study, we evaluated the anti-inflammatory activity with pharmacokinetic, ulcerogenic properties of various synthesized prodrugs of ibuprofen in experimental animals. Prodrugs 2, 6, 9, 10, 12, and 14 were found to possess significant anti-inflammatory activity with almost non-ulcerogenic potential than standard drug ibuprofen 1a in both normal and inflammation-induced rats. Metabolic stability of prodrugs 2, 6, 9, 10, 12, and 14 were also studied in rat liver microsomes and oral bioavailability was determined by estimating area under curve (AUC) and plasma concentration of these prodrugs at various time intervals. The experimental findings elicited higher AUC and plasma concentration at 1 and 2 h indicating improved oral bioavailability as compared to parent ibuprofen. These prodrugs are found to have least gastric ulceration with retain anti-inflammatory activity observed in experimental animals. Therefore, present experimental findings demonstrated significant improvement of various pharmacokinetic properties with least ulcerogenic potential of ester prodrugs of ibuprofen an anti-inflammatory agent
