4221-99-2

Basic information

• Product Name: (S)-(+)-2-Butanol
• Synonyms: (S)-(+)-sec-Butanol,99%;(S)-(+)-2-Butanol,(S)-(+)-sec-Butyl alcohol;(S)-(+)-sec-Butanol, 99% 1GR;(2S)-(+)-2-Hydroxybutane, (S)-(+)-sec-Butyl alcohol;(2S)-(+)-Butan-2-ol;(S)-(+)-2-Butanol ChiPros(R), produced by BASF, 99%;(S)-butan-2-ol;2-Butanol, (S)-
• CAS NO: 4221-99-2
• Molecular Formula: C₄H₁₀O
• Molecular Weight: 74.12
• EINECS: 224-168-1
• Product Categories: Alcohols, Hydroxy Esters and Derivatives;Chiral Compounds;chiral;Chiral Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Chiral Building Blocks;Functional Materials;Simple Alcohols (Chiral);Synthetic Organic Chemistry
• Mol File: 4221-99-2.mol
• Article Data: 88

Chemical Properties

• Melting Point: -114 °C
• Boiling Point: 99-100 °C(lit.)
• Flash Point: 80 °F
• Appearance: Clear colorless/Liquid
• Density: 0.803 g/mL at 25 °C(lit.)
• Vapor Density: 2.6 (vs air)
• Vapor Pressure: 12.5 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.397(lit.)
• Storage Temp.: Flammables area
• PKA: 15.31±0.20(Predicted)
• Explosive Limit: 9.8%
• Water Solubility: 125 g/L (20 ºC)
• Stability: Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents, halogens.
• Merck: 14,1541
• BRN: 1718763
• CAS DataBase Reference: (S)-(+)-2-Butanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-Butanol(4221-99-2)
• EPA Substance Registry System: (S)-(+)-2-Butanol(4221-99-2)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37-67
• Safety Statements: 9-13-24-25-26-46-7/9-24/25
• RIDADR: UN 1120 3/PG 3
• WGK Germany: 1
• RTECS: EO1750000
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 4221-99-2(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-2-Butanol can be used:To synthesize chiral asymmetric perylene diimides (PDI) that spontaneously self-assemble into one-handed nanotubes that are photoconductive or fluorescent in nature.To synthesize bulky chiral vinyl monomers that can be radically polymerized to helical polymers with an excess screw sense.As chiral solvent to study excited state photo transfer of the photoacid, 5,8-dicyano-2-naphthol (DCN2) in chiral environment.

InChI:InChI=1/C4H10O/c1-3-4(2)5/h4-5H,3H2,1-2H3/t4-/m0/s1

Upstream product

• 78-92-2 iso-butanol 
• 6118-13-4 S-(+)-1-buten-3-ol 
• 78-93-3 butanone 
• 624-64-6 trans-2-Butene 
• 83681-52-1 (R)-(-)-ethyl 2-butyl-n-pentylboronate 
• 3004-76-0 sulfuric acid mono-(S)-sec-butyl ester 
• 7732-18-5 water 
• 4909-81-3 s-butyl benzoate 
• 58044-56-7 butan-2-O-β-D-glucopyranoside 
• 106-88-7 (R)-(+)-1,2-epoxybutane 
• 76-05-1 trifluoroacetic acid 
• 67-63-0 isopropyl alcohol 
• 106-97-8 n-butane 
• 123-20-6 vinyl n-butyrate 

Downstream Products

• 589-40-2 sec-butyl formate 
• 88736-76-9 (S)-4-chloro-butyric acid sec-butyl ester 
• 33013-98-8 phenylcarbamic acid sec-butyl ester 
• 103275-78-1 benzenesulfonic acid-((S)-sec-butyl ester) 
• 50896-54-3 (S)-(+)-1-methylpropyl p-toluenesulfonate 
• 7504-61-2 (-)-Tris-sek.-butyl-phosphit 
• 4909-79-9 (+)-Dimethyl-formamid-di-sec.-butyl-acetal 
• 91799-57-4 (S)-sec-butyl 4-bromobenzenesulfonate 
• 152426-80-7 C₁₇H₂₀O₄S₂ 
• 128947-06-8 (R)-Fluoro-phenyl-acetic acid (S)-sec-butyl ester 
• 78-93-3 butanone 
• 134919-39-4 1,3-Dicyclohexyl-1-(3-{5-[3-ethyl-4-methyl-5-oxo-1,5-dihydro-pyrrol-(2Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrol-3-yl}-propionyl)-urea 
• 135027-89-3 xanthobilirubic acid (S)-sec-butyl ester 
• 135027-88-2 xanthobilirubic acid (R)-sec-butyl ester 

Relevant articles and documents

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Stereospecificity of hydrogen transfer by the NAD+-linked alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123

Investigation of the stereochemistry of the hydride transfer in reactions catalyzed by the recently isolated NAD+-linked alcohol dehydrogenase from the Antarctic psychrophile Moraxella sp. TAE123 was accomplished by using 1H NMR spectroscopy of the deuterated coenzyme. It was found that this new psychrophilic enzyme is a type A dehydrogenase. Moraxella sp. ADH reduces stereospecifically 2-butanone to produce (S)-2-butanol.

Novel highly efficient absolute optical resolution method by serial combination of two asymmetric reactions from acetylene monomers having racemic substituents

For general optical resolution, an optical resolution agent is necessary, and the best agent should be selected for each racemic compound. In this study, we will report that a novel optical resolution method by circularly polarized light (CPL) without any

Synthesis of cis-1,2-diol-type chiral ligands and their dioxaborinane derivatives: Application for the asymmetric transfer hydrogenation of various ketones and biological evaluation

Two cis-1,2-diol-type chiral ligands (T1 and T2) and their tri-coordinated chiral dioxaborinane (T(1–2)B(1–2)) and four-coordinated chiral dioxaborinane adducts with 4-tert-butyl pyridine sustained by N → B dati