422550-94-5

Basic information

• Product Name: 1-[3-Benzyl-5-(1,1-dioxoisothiazolidin-2-ylmethyl)phenyl]-1-(8-hydroxy-1,6-naphthyridin-7-yl)methanone
• Synonyms: Methanone, (3-((1,1-dioxido-2-isothiazolidinyl)methyl)-5-(phenylmethyl)phenyl)(8-hydroxy-1,6-naphthyridin-7-yl)-; 1,6-Naphthyridine A; {3-benzyl-5-[(1,1-dioxido-1,2-thiazolidin-2-yl)methyl]phenyl}(8-hydroxy-1,6-naphthyridin-7-yl)methanone
• CAS NO: 422550-94-5
• Molecular Formula: C₂₆H₂₃N₃O₄S
• Molecular Weight: 473.5435
• Mol File: 422550-94-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 762.8°C at 760 mmHg
• Flash Point: 415.1°C
• Density: 1.388g/cm³
• Vapor Pressure: 4.32E-24mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: 1-[3-Benzyl-5-(1,1-dioxoisothiazolidin-2-ylmethyl)phenyl]-1-(8-hydroxy-1,6-naphthyridin-7-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-Benzyl-5-(1,1-dioxoisothiazolidin-2-ylmethyl)phenyl]-1-(8-hydroxy-1,6-naphthyridin-7-yl)methanone(422550-94-5)
• EPA Substance Registry System: 1-[3-Benzyl-5-(1,1-dioxoisothiazolidin-2-ylmethyl)phenyl]-1-(8-hydroxy-1,6-naphthyridin-7-yl)methanone(422550-94-5)

Safety Data

• Hazardous Substances Data: 422550-94-5(Hazardous Substances Data)

Upstream product

• 422550-95-6 3-[({2-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-2-oxo-ethyl}-benzyloxycarbonyl-amino)-methyl]-pyridine-2-carboxylic acid ethyl ester 
• 1026627-33-7 {2-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-2-oxo-ethyl}-(2-chloro-pyridin-3-ylmethyl)-carbamic acid benzyl ester 
• 317335-30-1 1-[3-benzyl-5-(1,1-dioxo-isothiazolidin-2-ylmethyl)-phenyl]-ethanone 
• 500732-66-1 2-(3-benzyl-5-bromo-benzyl)-isothiazolidine 1,1-dioxide 
• 317334-60-4 (3-benzyl-5-bromo-phenyl)-methanol 
• 251966-71-9 (3-benzyl-5-bromo)benzyl bromide 
• 317334-59-1 3-benzyl-5-bromobenzaldehyde 
• 500732-62-7 3-azidomethyl-2-chloro-pyridine 
• 205744-14-5 C-(2-chloro-pyridin-3-yl)-methylamine 
• 100-52-7 benzaldehyde 
• 51339-31-2 3,5-dibromo-benzhydrol 
• 71572-36-6 3-benzyl-1,5-dibromobenzene 
• 626-39-1 1,3,5-trisbromobenzene 
• 42330-59-6 (2-chloropyrid-3-yl)methanol 

Relevant articles and documents

Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors

Certain aza- and polyaza-naphthalenyl ketones including certain quinolinyl and naphthyridinyl ketones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment or the delay in the onset of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.