42337-03-1

Basic information

• Product Name: 1-benzo[1,3]dioxol-5-yl-but-3-en-1-ol
• CAS NO: 42337-03-1
• Molecular Weight: 192.214
• Mol File: 42337-03-1.mol
• Article Data: 45

Chemical Properties

• CAS DataBase Reference: 1-benzo[1,3]dioxol-5-yl-but-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzo[1,3]dioxol-5-yl-but-3-en-1-ol(42337-03-1)
• EPA Substance Registry System: 1-benzo[1,3]dioxol-5-yl-but-3-en-1-ol(42337-03-1)

Safety Data

• Hazardous Substances Data: 42337-03-1(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 107-05-1 3-chloroprop-1-ene 
• 1730-25-2 allylmagnesium bromide 
• 24850-33-7 allyltributylstanane 
• 556-56-9 allyl iodid 
• 191732-48-6 (E)-(3-bromoprop-1-en-1-yl)tributylstannane 
• 591-87-7 Allyl acetate 
• 106-95-6 allyl bromide 
• 107-18-6 allyl alcohol 

Downstream Products

• 94-53-1 Piperonylic acid 
• 120-57-0 piperonal 
• 5420-97-3 1-acetoxy-1-(3',4'-methylenedioxyphenyl)but-3-ene 
• 406486-91-7 4β-acetoxy-2β,6β-diethyl-tetrahydropyran 
• 1242077-06-0 (E)-1-(4-(benzo[d][1,3]dioxol-5-yl)but-3-en-2-yl)-4-phenyl-1H-1,2,3-triazole 
• 143503-94-0 rac-1-(benzo[d][1,3]dioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)butan-1-ol 
• 56438-69-8 rac-1-(benzo[d][1,3]dioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)butan-1-one 
• 1449790-07-1 3-(1,3-benzodioxol-5-yl)-6-(2-bromophenyl)hex-1-en-3-ol 
• 1449790-06-0 2-(1,3-benzodioxol-5-yl)-5-(2-bromophenyl)pentan-2-ol 
• 1449790-03-7 1-(1,3-benzodioxol-5-yl)-4-(2-bromo-5-methoxyphenyl)butan-1-ol 
• 1449789-97-2 1-(1,3-benzodioxol-5-yl)-4-(2-bromophenyl)butan-1-ol 
• 1449789-93-8 1-(1,3-benzodioxol-5-yl)-4-(2-bromo-5-methoxyphenyl)butan-1-one 
• 1449789-87-0 C₁₇H₁₅BrO₃ 
• 63814-03-9 1,2,3,3a,4,5,12b,12c-octahydro-7H-1,3-benzodioxolo[5,6-c]pyrrolo[3,2,1-ij]quinoline 

Relevant articles and documents

Photoredox Allylation Reactions Mediated by Bismuth in Aqueous Conditions

Organometallic allylic reagents are widely used in the construction of C?C bonds by Barbier-type reactions. In this communication, we have described a photoredox Barbier allylation of aldehydes mediated by bismuth, in absence of other metals as co-reductants. Mild reaction conditions, tolerance of oxygen, and use of aqueous solvent make this photoredox methodology attractive for green and sustainable synthesis of homoallylic alcohols.

Cu-catalyzed hydroxycyclopropanol ring-opening cyclization to tetrahydrofurans and tetrahydropyrans: short total syntheses of hyperiones

Tetrahydrofurans (THFs) and tetrahydropyrans (THPs) are important core scaffolds frequently found in many molecules of medicinal importance. Herein, we report a novel copper-catalyzed hydroxycyclopropanol ring-opening cyclization methodology to synthesize di- or tri-substituted THFs and THPs. In this reaction, a strained C-C bond was cleaved and a new Csp3-O bond was formed to produce the aforementioned O-heterocycles. The new THF synthesis features a broad substrate scope, scalability, and good functional-group tolerability. It enabled us to complete the shortest enantioselective syntheses of hyperiones A and B (3 and 4 steps, respectively), which is significantly shorter than the previously reported two total syntheses (≥10 steps).

Photocatalytic Umpolung Synthesis of Nucleophilic π-Allylcobalt Complexes for Allylation of Aldehydes

The concept of "umpolung"reactivity of π-allylmetal complexes has been developed as a powerful method for the allylation of aldehydes. This paper describes the photocatalytic umpolung strategy for the synthesis of nucleophilic allylcobalt complexes through a single-electron-transfer (SET) process. This strategy enables the metallaphotoredox allylation of carbonyls with allyl acetate using organic N,N-diisopropylethylamine as the terminal reductant bypassing the use of a stoichiometric amount of metals. Ultraviolet-visible spectroscopy was used to monitor the redox changes of cobalt in the reaction.