4235-20-5

Basic information

• Product Name: 2-Amino-4-chlorodiphenylsulfide
• Synonyms: 5-chloro-2-phenylsulfanylaniline
• CAS NO: 4235-20-5
• Molecular Formula: C₁₂H₁₀ClNS
• Molecular Weight: 235.73
• Mol File: 4235-20-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 375.5°C at 760 mmHg
• Flash Point: 180.9°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 7.72E-06mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: 2-Amino-4-chlorodiphenylsulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-chlorodiphenylsulfide(4235-20-5)
• EPA Substance Registry System: 2-Amino-4-chlorodiphenylsulfide(4235-20-5)

Safety Data

• Hazardous Substances Data: 4235-20-5(Hazardous Substances Data)

Usage

General Description

2-Amino-4-chlorodiphenylsulfide, also known as AC540, is a chemical compound with the molecular formula C12H10ClNS. It is a white to slightly yellow powder, and is primarily used as a fungicide and bactericide in the agricultural industry. AC540 is effective against a wide range of plant pathogens, and is commonly used to protect crops such as rice, potatoes, and vegetables from diseases. It works by inhibiting the growth and reproduction of fungi and bacteria, thereby preventing the spread of infections. AC540 is considered to be relatively low in toxicity and has a low potential for bioaccumulation, making it an attractive option for agricultural use. However, it is important to handle and use this chemical with care, as it can be harmful if ingested or inhaled, and may cause skin and eye irritation.

InChI:InChI=1/C12H10ClNS/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8H,14H2

Upstream product

• 591-50-4 iodobenzene 
• 1004-00-8 4-chloro-2-aminobenzenethiol 
• 345-18-6 2-fluoro-5-chloronitrobenzene 
• 108-98-5 thiophenol 
• 4548-56-5 4-chloro-2-nitrophenyl phenyl sulfide 

Downstream Products

• 1451261-59-8 N-[5-chloro-2-(phenylsulfanyl)phenyl]-1-benzofuran-2-sulfonamide 
• 1451261-60-1 N-[5-chloro-2-(phenylsulfonyl)phenyl]-1-benzofuran-2-sulfonamide 
• 180145-03-3 (5-Chloro-2-phenylsulfanyl-phenyl)-(3-chloro-propyl)-amine 
• 1100794-07-7 (4-chloro-2-iodophenyl)(phenyl)sulfane 
• 1100793-97-2 5-chloro-2-(phenylthio)phenol 
• 1100793-89-2 N-[5-chloro-2-(phenylthio)phenyl]-3-(4-methylpiperazine-1-yl)-propanamidine 
• 1103976-20-0 C₁₇H₁₂ClNO₂S 
• 1103976-09-5 C₁₆H₁₀ClNO₂S 

Relevant articles and documents

Nickel-Catalyzed C?H Chalcogenation of Anilines

The C?H thiolation of aniline derivatives was accomplished with a versatile nickel(II) catalyst under ligand-free conditions. The robust nature of the nickel catalysis system was reflected by the C?H thiolation with a good functional group tolerance and an ample scope, employing anilines possessing removable directing groups. The widely applicable nickel catalyst also allowed for aniline C?H selenylations, while mechanistic studies provided strong support that the rate-determining step is the C?H activation.

BENZOFURAN-2-SULFONAMIDES DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

The present invention relates to novel benzofuran-2-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.

Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide

Quaternization of the nitrogen atom of 2-amino-4-chlorophenyl phenyl sulfide analogues of chlorpromazine improved inhibition ～40-fold (3′,4′-dichlorobenzyl-[5-chloro-2-phenylsulfanylphenylamino)-propyl] -dimethylammonium chloride inhibited trypanothione r