4241-73-0

Basic information

• Product Name: D-Glucose isonicotinoyl hydrazone
• Synonyms: D-Glucose isonicotinoyl hydrazone;Isonicotinic acid hydrazide D-glucose hydrazone
• CAS NO: 4241-73-0
• Molecular Formula: C12H17N3O6
• Molecular Weight: 299.32
• Mol File: 4241-73-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 440.61°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.2920 (rough estimate)
• Refractive Index: 1.5290 (estimate)
• CAS DataBase Reference: D-Glucose isonicotinoyl hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: D-Glucose isonicotinoyl hydrazone(4241-73-0)
• EPA Substance Registry System: D-Glucose isonicotinoyl hydrazone(4241-73-0)

Safety Data

• Hazardous Substances Data: 4241-73-0(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 50-99-7 D-glucose 

Relevant articles and documents

Kinetic studies of the interaction between isoniazid and reducing sugars

The interaction between isoniazid and reducing sugars is acid-catalyzed and reversible. Kinetic studies of hydrazone formation from isoniazid and glucose, lactose, maltose, and galactose have been carried out in simulated gastric juice at 37°C. The forward reaction was found to follow second-order kinetics, while the reverse reaction, the hydrolysis of the sugar isonicotinoyl hydrazone, is pseudo-first-order. The effects of the concentration of reactants, pH, and temperature on the rate have been studied, and the rate constants and the energy of activation were determined.