426219-43-4

Basic information

• Product Name: 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI)
• Synonyms: 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI);5H-pyrrolo[1,2-c]imidazol-7(6H)-one;5,6-Dihydto-7H-pyrrolo[1,2-c]iMidazol-7-one;7H-Pyrrolo[1,2-c]iMidazol-7-one,5,6-dihydro-;5,6-Dihydro-7H-pyrrolo[1,2-c]iMidazol-7-one;5H-pyrrolo[1,2-c]imidazole-7(6H)-one
• CAS NO: 426219-43-4
• Molecular Formula: C₆H₆N₂O
• Molecular Weight: 122.12464
• Product Categories: PYRROLIDINE;AMINETERTIARY
• Mol File: 426219-43-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 342.489 °C at 760 mmHg
• Flash Point: 160.932 °C
• Appearance: /
• Density: 1.443 g/cm³
• Storage Temp.: 2-8°C
• PKA: 3.83±0.20(Predicted)
• CAS DataBase Reference: 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI)(426219-43-4)
• EPA Substance Registry System: 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI)(426219-43-4)

Safety Data

• Hazardous Substances Data: 426219-43-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI)" is a heterocyclic organic compound with a complex molecular structure. It belongs to the class of imidazoles and contains a pyrroloimidazole core. 7H-Pyrrolo[1,2-c]imidazol-7-one,5,6-dihydro-(9CI) is known for its potential biological activities and is a valuable building block in medicinal and pharmaceutical chemistry. Its unique structure and reactivity make it a key component in the synthesis of various biologically active molecules and pharmaceutical products. Despite its complex name and structure, this compound has great importance in the field of organic and medicinal chemistry due to its versatile properties and potential applications in drug development and research.

Upstream product

• 57531-35-8 C₆H₆N₂O 
• 1346155-45-0 3-bromo-1-(1H-imidazol-4-yl)-1-propanone hydrobromide 
• 1346218-36-7 3-bromo-1-(1H-imidazol-4-yl)-1-propanone 

Downstream Products

• 426219-52-5 7-(4-bromophenyl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-ol 
• 426219-15-0 (+/-)-7-(5-fluorobenzo[b]thiophen-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-ol 
• 426219-18-3 orteronel 
• 566939-85-3 Orteronel 
• 752243-39-3 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide 
• 426219-53-6 2C₁₀H₁₁NO₅*C₁₈H₁₇N₃O₂ 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING

Provided herein are compounds having activity against TTR related conditions, and pharmaceutically accepted salts and solvates thereof. Also provided are methods of using the compounds for inhibiting and preventing TTR aggregation and/or amyloid formation in the peripheral nerves, kidney, cardiac tissue, eye and CNS, and of treating a subject with peripheral TTR amyloidosis.

Novel imidazole derivatives, production method thereof and use thereof

The present invention provides a compound having a steroid C17,20-lyase-inhibitory activity and useful for the therapy and prophylaxis of tumor such as prostatism, breast cancer and the like, and a method for efficiently separating an optically active compound of this compound from a mixture of optical isomers thereof, a compound of the formula: wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof, and a method for obtaining an optically active compound by optically resolving a mixture of optical isomers by the use of a resolving agent such as tartranilic acid and the like.