4270-65-9

Basic information

• Product Name: Acetamide, N-(chloromethyl)-N-methyl-
• CAS NO: 4270-65-9
• Molecular Formula: C4H8ClNO
• Molecular Weight: 121.567
• Mol File: 4270-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(chloromethyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(chloromethyl)-N-methyl-(4270-65-9)
• EPA Substance Registry System: Acetamide, N-(chloromethyl)-N-methyl-(4270-65-9)

Safety Data

• Hazardous Substances Data: 4270-65-9(Hazardous Substances Data)

Upstream product

• 80179-40-4 N-<(Dimethylamino)methyl>-N-methylacetamid 
• 80179-42-6 N-<(Diethylamino)methyl>-N-methylacetamid 

Downstream Products

• 51164-31-9 (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid (acetyl-methyl-amino)-methyl ester 
• 40286-78-0 N-(benzoyloxy)methyl,N-methylacetamide 

Relevant articles and documents

Acyl Halide Induced Cleavage of N-Acylated Aminals

Acyl halides attack N-acylated aminals 6 at the amine nitrogen as well as at the carboxamide group to form either N-halomethyl carboxamides 5 besides N,N-dialkyl carboxamides 11, or diacylamines 12 besides N,N-dialkylmethaneiminium halides 4.Depending on the variation of the substituents on both heteroatoms the cleavage may be directed to follow only one or the other pathway.Of highly synthetic interest is the broadly applicable preparation of methaneiminium salts 4 having bulky substituents on nitrogen by means of cleavage of the corresponding N,N-dialkyl-N'-formyl-N'-methylmethanediamines 6.