4274-26-4Relevant articles and documents
Anti-babesial and anti-plasmodial compounds from Phyllanthus niruri
Subeki,Matsuura, Hideyuki,Takahashi, Kosaku,Yamasaki, Masahiro,Yamato, Osamu,Maede, Yoshimitsu,Katakura, Ken,Kobayashi, Sumiko,Trimurningsih,Chairul,Yoshihara, Teruhiko
, p. 537 - 539 (2005)
Bioassay-guided fractionation of boiled aqueous extracts from the whole plant of Phyllanthus niruri led to the isolation of 1-O-galloyl-6-O-luteoyl- α-D-glucose (1), with IC50 values of 4.7 μg/mL against Babesia gibsoni and 1.4 μg/mL against Plasmodium falciparum in vitro. The known compounds β-glucogallin (2), quercetin 3-O-β-D-glucopyranosyl- (2→1)-O-β-D-xylopyranoside (3), β-sitosterol, and gallic acid were also isolated. Structures of these compounds were elucidated on the basis of their chemical and spectroscopic data.