42748-90-3 Usage
Properties
Derivative of pyrimidinone
Chlorine atom attached to the 5-position of the pyrimidine ring
Used as an intermediate in the synthesis of various medications
Studied for potential antiviral and antibacterial properties
Can be used as a building block in the production of other organic compounds
Monohydrochloride salt form provides improved solubility and stability
Specific content
2(1H)-Pyrimidinone, 5-chloro-, monohydrochloride is a chemical compound with the molecular formula C4H4ClN2O·HCl.
It is a derivative of pyrimidinone, with a chlorine atom attached to the 5-position of the pyrimidine ring.
The compound is used in the pharmaceutical industry as an intermediate in the synthesis of various medications.
It has also been studied for its potential antiviral and antibacterial properties.
2(1H)-Pyrimidinone, 5-chloro-, monohydrochloride can be used as a building block in the production of other organic compounds.
The monohydrochloride salt form of this compound provides improved solubility and stability, making it easier to handle and use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 42748-90-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,4 and 8 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 42748-90:
(7*4)+(6*2)+(5*7)+(4*4)+(3*8)+(2*9)+(1*0)=133
133 % 10 = 3
So 42748-90-3 is a valid CAS Registry Number.
42748-90-3Relevant articles and documents
Substituted pyrimidin-2-ones and the salts thereof
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, (2008/06/13)
Compounds of the general formula: STR1 wherein X represents halogen or trifluoromethyl; R1 and R2, independently represent hydrogen or lower alkyl; R3, R4 and R5, which may be the same or different, each represent hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkanoyl, lower alkenoyl, C7-16 aralkyl or C6-10 aryl or a 5-9 membered unsaturated or aromatic heterocyclic ring; one or both of R4 and R5 may also represent aroyl groups; Z represents an oxygen atom or a sulfur atom or oxide thereof or a group NR6 (wherein R6 is as defined for R hereinafter or represents the group COR7 in which R7 represents hydrogen or optionally substituted aryl, heterocyclic, aralkyl, lower alkyl or lower alkoxy group; and R represents a C6-10 carbocyclic aromatic group or a heterocyclic group containing a 5-9 membered unsaturated or aromatic heterocyclic ring which ring contains one or more heteroatoms selected from O, N and S and optionally carries a fused ring which carbocyclic or heterocyclic group may carry one or more C1-4 alkyl or phenyl groups said groups being optionally substituted; and where acid or basic groups are present, the salts thereof are useful in combating abnormal cell proliferation. The compounds of the invention are prepared by inter alia alkylation, ring closure and oxidation.
