42872-23-1

Basic information

• Product Name: [4‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone
• Synonyms: [4‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone
• CAS NO: 42872-23-1
• Molecular Weight: 287.361
• Mol File: 42872-23-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [4‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [4‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone(42872-23-1)
• EPA Substance Registry System: [4‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone(42872-23-1)

Safety Data

• Hazardous Substances Data: 42872-23-1(Hazardous Substances Data)

Upstream product

• 106-43-4 para-chlorotoluene 
• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 29540-83-8 p-tolyl triflate 
• 3899-96-5 4-methylphenyl tosylate 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 106-49-0 p-toluidine 
• 134-85-0 4-chlorobenzophenone 

Relevant articles and documents

Sodium Butylated Hydroxytoluene: A Functional Group Tolerant, Eco-Friendly Base for Solvent-Free, Pd-Catalysed Amination

NaBHT (sodium 2,6-di-tert-butyl-4-methylphenolate), a strong, but hindered and lipophilic base, has been effectively paired with similarly lipophilic, high-reactivity Pd-NHC (N-heterocyclic carbene) catalysts to produce an ideal combination for performing

Stable nickel(0) phosphites as catalysts for C-N cross-coupling reactions

Herein we describe the design and preparation of inexpensive, air-stable nickel phosphite-based catalysts for use in the C-N cross-coupling reaction. The combination of nickel tetrakis(triphenyl phosphite) {Ni[P(OPh) 3]4} and 1,1'-bis(diphenylphosphino)ferrocene (dppf), and in particular a newly developed catalyst (dppf)Ni[P(OPh)3] 2, were found to be extremely effective in catalyzing a range of amination reactions of anilines and amines with aryl chlorides. This new catalyst system offers an alternative to the bis(cyclooctadienyl)nickel [Ni(COD)2] and palladium(0) catalysts commonly used for C-N bond formation.

Aminations of aryl bromides in water at room temperature

Unsymmetrical di- and triarylamines can be formed under green chemistry conditions, taking advantage of micellar catalysis leading to palladium-catalyzed aminations at ambient temperatures in water as the only medium.