430-99-9

Basic information

• Product Name: 2-FLUOROACRYLIC ACID
• Synonyms: 2-FLUOROACRYLIC ACID;2-FLUOROPROPENOIC ACID;2-FLUOROACRYLIC ACID 97%;2-Fluoroprop-2-enoic acid;2-Propenoic acid, 2-fluoro-;1g, 2g, 5g;alpha-Fluoroacrylic acid
• CAS NO: 430-99-9
• Molecular Formula: C₃H₃FO₂
• Molecular Weight: 90.05
• Mol File: 430-99-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 51.5 °C
• Boiling Point: 181.3 °C at 760 mmHg
• Flash Point: 63.5 °C
• Appearance: /
• Density: 1.233 g/cm³
• Vapor Pressure: 0.397mmHg at 25°C
• Refractive Index: 1.388
• Storage Temp.: 2-8°C
• PKA: pK1:2.55 (25°C)
• CAS DataBase Reference: 2-FLUOROACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUOROACRYLIC ACID(430-99-9)
• EPA Substance Registry System: 2-FLUOROACRYLIC ACID(430-99-9)

Safety Data

• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• HazardClass: IRRITANT
• Hazardous Substances Data: 430-99-9(Hazardous Substances Data)

Usage

Uses

2-Fluoroacrylic Acid is a monomeer used for the preparation of fluoropolymers . It is also used a s a reactant for the preparation of fluorolactams.

InChI:InChI=1/C3H3FO2/c1-2(4)3(5)6/h1H2,(H,5,6)

Upstream product

• 67-56-1 methanol 
• 2317-91-1 1-chloro-1-fluoroethane 
• 201230-82-2 carbon monoxide 
• 420-25-7 1-bromo-1-fluoroethylene 
• 760-80-5 ethyl 2-fluoroacrylate 

Downstream Products

• 21133-78-8 4-Nitro-α-chlor-α-fluor-dihydrozimtsaeure 
• 16522-55-7 α-fluoroacryloyl chloride 
• 1443236-32-5 ethyl 4-{3-{(2-fluoroacryloyl)amino}phenyl}-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate 
• 664342-21-6 N-benzyl-N-(but-3-enyl)-α-fluoroacrylamide 
• 664342-20-5 N-allyl-N-benzyl-2-fluoroacrylamide 

Relevant articles and documents

METHOD FOR PRODUCING alpha-FLUOROACRYLIC ACID

An object of the present invention is to provide a novel method for producing an α-fluoroacrylic acid ester compound. This problem is solved by a method for producing a compound represented by formula (1), wherein R1 and R2 are identical or different, and each represents an alkyl group or the like; and R3 is an alkyl group or the like, the method comprising step A of reacting a compound represented by formula (2) with R3—OH (3) and carbon monoxide in the presence of palladium, a double bond-containing compound (α), a diphosphine compound (β), and a base, to obtain the compound represented by formula (1) above.

Low-temperature 19F NMR spectroscopy of 1-fluoro-1-lithioethenes - Stability, shifts and unexpected coupling constants

Half-lives and fluorine atom shifts of stabilized 1-fluoro-l-lithioethenes bearing hydrogen, fluorine, phenyl, and/or dimethylphenylsilyl groups in the β-positions have been determined by a low-temperature 19F NMR spectroscopy. Some 1-fluoro-1-lithioethenes displayed an exceptionally low value of the trans-3JFF coupling constant. Stereoselectivity of carbenoid formation, as well as an effect of configuration on the stability is discussed.