43083-10-9Relevant articles and documents
Concise Total Syntheses of dl-Camptothecin and Related Anticancer Drugs
Shen, Wang,Coburn, Craig A.,Bornmann, William G.,Danishefsky, Samuel J.
, p. 611 - 617 (2007/10/02)
The readily available tricyclic ester 10 has been converted to dl-camptothecin (1) in 39percent yield.It was discovered that, with the C5 carbomethoxy group in place, the C6 benzylic position of 10 (pyridone numbering) is selectively