4316-51-2Relevant articles and documents
Triptycene carbene palladium compound and application thereof
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Paragraph 0083-0090, (2021/05/08)
The invention discloses a triptycene carbene palladium compound and an application thereof, the structural formula of the triptycene carbene palladium compound is represented by a formula I or a formula II; compared with a conventional metal palladium catalyst, the triptycene carbene palladium compound is simple and convenient to prepare, high in yield and suitable for various substrates, the usage amount of the catalyst can be reduced to one ten thousandth, and the triptycene carbene palladium compound has a good catalytic effect on various metal palladium catalytic reactions; and the triptycene carbene palladium compound has important application value for researching the progress and application of catalytic reaction.
Triptycene carbene palladium pyridine complex and application thereof
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Paragraph 0044-0050, (2021/06/12)
The invention relates to a triptycene carbene palladium pyridine complex and application thereof. The structural formula of the triptycene carbene palladium pyridine complex is shown as a formula I. The complex provided by the invention is correct in detection. Based on the defects that a metal catalyst used for organic reaction at the present stage cannot be suitable for various substrates, the catalyst in use amount and cost and is difficult to preserve for a long time, the invention provides the triptycene carbene palladium pyridine complex used as a catalyst, wherein the preparation is simple and convenient, the yield is high, the triptycene carbene palladium pyridine complex is suitable for various substrates, the usage amount of the catalyst can be reduced to one ten thousandth, and the triptycene carbene palladium pyridine complex has a better catalytic effect on various metal palladium catalytic reactions. The triptycene carbene palladium pyridine complex has important application value for researching the progress and application of catalytic reaction.
A Pd/Cu-Free magnetic cobalt catalyst for C-N cross coupling reactions: synthesis of abemaciclib and fedratinib
Hajipour, Abdol R.,Khorsandi, Zahra,Sarfjoo, Mohamad Reza,Varma, Rajender S.
supporting information, p. 5222 - 5229 (2021/07/29)
Herein, the synthesis of a nano-catalytic system comprising magnetic nanoparticles as the core and edible natural ligands bearing functional groups as supports for cobalt species is described. Subsequent to its characterization, the efficiency of the catalyst was investigated for C-N cross-coupling reactions using assorted derivatives of amines and aryl halides. This novel and easily accessible Pd- and Cu-free catalyst exhibited good catalytic activity in these reactions using γ-valerolactone (GVL) at room temperature; good recyclability bodes well for the future application of this strategy. The introduced catalytic system is attractive in view of the excellent efficiency in an array of coupling reactions and its versatility is illustrated in the synthesis of abemaciclib and fedratinib, which are FDA-approved new and significant anti-cancer medicinal compounds that are prepared under green reaction conditions.