432-88-2

Basic information

• Product Name: 1,1-Difluoro-2-phenylpropan-2-ol 97%
• Synonyms: 1,1-Difluoro-2-phenylpropan-2-ol 97%;1,1-Difluoro-2-phenylpropan-2-ol97%
• CAS NO: 432-88-2
• Molecular Formula: C₉H₁₀F₂O
• Molecular Weight: 172.1719064
• Mol File: 432-88-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 81 °C(Press: 7 Torr)
• Appearance: /
• Density: 1.160±0.06 g/cm3(Predicted)
• PKA: 12.26±0.29(Predicted)
• CAS DataBase Reference: 1,1-Difluoro-2-phenylpropan-2-ol 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Difluoro-2-phenylpropan-2-ol 97%(432-88-2)
• EPA Substance Registry System: 1,1-Difluoro-2-phenylpropan-2-ol 97%(432-88-2)

Safety Data

• Hazardous Substances Data: 432-88-2(Hazardous Substances Data)

Usage

Common uses

Reagent in organic synthesis
Solvent in various chemical reactions

Color

Colorless

State

Liquid

Odor

Faint

Solubility

Soluble in water and organic solvents

Flammability

Flammable

Safety precautions

Potential for skin, eye, and respiratory irritation
Store in a well-ventilated area
Keep away from sources of ignition

Industrial applications

Building block for drug synthesis in the pharmaceutical industry
Intermediate in the production of other chemicals

Upstream product

• 431-05-0 1,1-difluoroacetone 
• 1093490-29-9 diethyl 1,1-difluoro-2-hydroxy-2-phenylpropylphosphonate 
• 6699-93-0 (2-methylphenyl)lithium 
• 703-42-4 2,2-difluoro-1-(o-tolyl)ethan-1-one 
• 113453-93-3 Difluormethyl-methyl-o-tolyl-carbinol 
• 98-86-2 acetophenone 
• 861721-54-2 1,1-difluoro-2-phenyl-1-(phenylsulfonyl)propan-2-ol 
• 1008-05-5 1-(3,3-difluoroprop-1-en-2-yl)-2-methylbenzene 
• 917-54-4 methyllithium 

Downstream Products

• 345-60-8 α-(difluoromethyl)styrene 

Relevant articles and documents

Aromatic fluorocopolymers based on α-(difluoromethyl)styrene and styrene: Synthesis, characterization, and thermal and surface properties

A study on the α-(difluoromethyl)styrene (DFMST) reactivity under conventional radical copolymerization conditions is presented. Although the homopolymerization of DFMST failed, its radical bulk copolymerization with styrene (ST) led to the synthesis of f

Nucleophilic difluoromethylation and difluoromethylenation of aldehydes and ketones using diethyl difluoromethylphosphonate

New methodology for difluoromethylation and difluoromethylenation of aldehydes and ketones based on nucleophilic fluorination using diethyl difluoromethylphosphonate (1) was developed.

Nucleophilic difluoromethylation of carbonyl compounds using TMSCF 2SO2Ph and Mg0-mediated desulfonylation

A new nucleophilic difluoromethylation chemistry using fluoride-induced (phenylsulfonyl)difluoromethylation with TMSCF2SO2Ph followed by the magnesium-metal-mediated desulfonylation has been achieved. This methodology is compatible w