4344-61-0 Usage
General Description
1H-Benzimidazole,1-methyl-2-(methylthio)-, also known as methylsultinine, is a chemical compound with the molecular formula C9H10N2S. It is a white to off-white crystalline powder that is commonly used as a pharmaceutical intermediate. Methylsultinine exhibits anti-inflammatory, analgesic, and antipyretic properties, making it a valuable ingredient in the production of various medicinal products. It is also used in the synthesis of other organic compounds, such as dyes, pesticides, and other pharmaceuticals. Methylsultinine should be handled and stored according to proper safety regulations and guidelines due to its toxic and irritant properties.
Check Digit Verification of cas no
The CAS Registry Mumber 4344-61-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,4 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4344-61:
(6*4)+(5*3)+(4*4)+(3*4)+(2*6)+(1*1)=80
80 % 10 = 0
So 4344-61-0 is a valid CAS Registry Number.
4344-61-0Relevant articles and documents
Methylenation for Aldehydes and Ketones Using 1-Methylbenzimidazol-2-yl Methyl Sulfone
Ando, Kaori,Oguchi, Mai,Kobayashi, Takahisa,Asano, Haruka,Uchida, Nariaki
, p. 9936 - 9943 (2020/09/04)
The methylenation reagent 1-methylbenzimidazol-2-yl methyl sulfone 2 reacts with various aldehydes and ketones in the presence of t-BuOK (room temperature, 1 h) in dimethylformamide to give the corresponding terminal alkenes generally in high yields. For sensitive substrates, the reaction is better carried out at low temperature using sodium hexamethyldisilazide in 1,2-dimethoxyethane. The byproduct is easily removed from the products, and the reaction conditions are mild and practical. Reagent 2 can be easily prepared from commercially available 2-mercaptobenzimidazole 5 in 95% yield without any expensive reagents.
