4371-02-2

Basic information

• Product Name: METHYLPHENYLMALONIC ACID
• Synonyms: METHYLPHENYLMALONIC ACID;2-METHYL-2-PHENYL-PROPANEDIOIC ACID
• CAS NO: 4371-02-2
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.18
• Mol File: 4371-02-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 367.6±30.0 °C(Predicted)
• Appearance: /
• Density: 1.335±0.06 g/cm3(Predicted)
• PKA: 2.82±0.10(Predicted)
• CAS DataBase Reference: METHYLPHENYLMALONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: METHYLPHENYLMALONIC ACID(4371-02-2)
• EPA Substance Registry System: METHYLPHENYLMALONIC ACID(4371-02-2)

Safety Data

• Hazardous Substances Data: 4371-02-2(Hazardous Substances Data)

Upstream product

• 37434-59-6 dimethyl 2-phenylmalonate 
• 101-41-7 benzeneacetic acid methyl ester 
• 62707-19-1 3-ethoxy-2-methyl-3-oxo-2-phenylpropanoic acid 
• 74-88-4 methyl iodide 
• 65749-05-5 2-methyl-2-phenylmalonic acid dimethyl ester 
• 492-37-5 hydratropic acid 
• 124-38-9 carbon dioxide 
• 34009-61-5 diethyl 2-methyl-2-phenylmalonate 

Downstream Products

• 492-37-5 hydratropic acid 
• 24131-01-9 2,2,5-trimethyl-5-phenyl-1,3-dioxane-4,6-dione 
• 109311-71-9 8-methyl-8-phenyl-6,10-dioxa-spiro[4.5]decane-7,9-dione 
• 150080-50-5 methyl-phenyl-malonyl chloride 
• 7782-24-3 (S)-2-Phenylpropionic acid 
• 7782-26-5 (R)-2-Phenylpropionic acid 
• 57585-22-5 racem.-2-Ethyl-4-phenyl-pentadien-(2,3)-carbonsaeure 
• 38701-09-6 2,3-pentadienoic acid, 2-ethyl-4-phenyl-, ethyl ester 
• 5717-44-2 α,γ-Dimethyl-γ-phenyl-allencarbonsaeure-ethylester 
• 36858-88-5 α,γ-Dimethyl-γ-phenyl-allencarbonsaeure 
• 101730-02-3 N-benzyl-2-methyl-2-phenyl-malonamic acid methyl ester 
• 55787-79-6 N-benzyl-2-methyl-2-phenyl-malonamic acid 
• 116140-68-2 (±)-2-methyl-2-phenylmalonic acid monomethyl ester 
• 193967-73-6 2-Methyl-2-phenyl-malonic acid bis-(3-nitro-phenyl) ester 

Relevant articles and documents

Thermolysis of 4-methyl-4-phenylmalonyl Peroxide: A New Oxygen Dependent Chemiluminescent Reaction

Thermolysis of 4-methyl-4-phenylmalonyl peroxide in acetonitrile is accelerated by electron donors, such as perylene.When both the perylene and oxygen are present in solution, the reaction gives acetophenone and a small amount of light.Investigation of th

Reactions of amino-substituted cyclodextrins with 2-arylpropanoic acid derivatives

Reactions of 6A-amino-6A-deoxy-β-cyclodextrin and 3A-amino-3A-deoxy-(2AS,3 AS)-β-cyclodextrin with the 3-nitrophenyl esters of 2-phenylpropanoic acid and Ibuprofen occur with only low diastereoselectivity, to afford the corresponding arylpropanamido-substituted cyclodextrins. These amides are also formed by decarboxylation of corresponding malonates, again with only low diastereoselectivity. The n.m.r. spectra of the amido-substituted cyclodextrins indicate that the aryl substituent is included within the cyclodextrin annulus at low temperature, but becomes dissociated from the cavity as the temperature is increased.