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4378-14-7

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4378-14-7 Usage

Chemical Properties

White Solid

Uses

(R,S)-Homocysteine thioether

Check Digit Verification of cas no

The CAS Registry Mumber 4378-14-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,7 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4378-14:
(6*4)+(5*3)+(4*7)+(3*8)+(2*1)+(1*4)=97
97 % 10 = 7
So 4378-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H17NO2S/c1-3-6(2)9-7(4-5-12)8(10)11/h6-7,9,12H,3-5H2,1-2H3,(H,10,11)

4378-14-7Relevant articles and documents

Rationally engineered variants of S-adenosylmethionine (SAM) synthase: Reduced product inhibition and synthesis of artificial cofactor homologues

Dippe,Brandt,Rost,Porzel,Schmidt,Wessjohann

supporting information, p. 3637 - 3640 (2015/03/30)

S-Adenosylmethionine (SAM) synthase was engineered for biocatalytic production of SAM and long-chain analogues by rational re-design. Substitution of two conserved isoleucine residues extended the substrate spectrum of the enzyme to artificial S-alkylhomocysteines. The variants proved to be beneficial in preparative synthesis of SAM (and analogues) due to a much reduced product inhibition. This journal is

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