438554-06-4

Basic information

• Product Name: 3-Nitro-4-(propylaMino)benzonitrile
• Synonyms: 3-Nitro-4-(propylaMino)benzonitrile
• CAS NO: 438554-06-4
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.21324
• Mol File: 438554-06-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Nitro-4-(propylaMino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitro-4-(propylaMino)benzonitrile(438554-06-4)
• EPA Substance Registry System: 3-Nitro-4-(propylaMino)benzonitrile(438554-06-4)

Safety Data

• Hazardous Substances Data: 438554-06-4(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 939-80-0 4-chloro-3-nitrobenzonitrile 
• 107-08-4 1-iodo-propane 
• 6393-40-4 4-Amino 3-nitro-benzonitrile 
• 556-53-6 N-propylamine hydrochloride 

Downstream Products

• 355022-39-8 4-(5-cyano-1-propyl-1H-benzoimidazol-2-yl)-benzoic acid 
• 355022-21-8 3-amino-4-(n-propylamino)benzonitrile 

Relevant articles and documents

Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI

A series of novel benzimidazole diamidines were prepared from the corresponding dicyano analogues either by applying Pinner methodology (5a–c, 10 and 13a) or by making amidoximes intermediates that were reduced to the corresponding amidines (15a–c). The n

BASIC AMINE COMPOUND AND USE THEREOF

Novel amine compounds which are represented by the following formula (1) and efficacious against diseases such as a viral infectious disease with HIV, rheumatism, and cancer metastasis; typically, A 1 and A 2 represent a hydrogen atom or a substitutable monocyclic or polycyclic heteroaromatic ring and W represents a substitutable benzene ring or any group represented by the following formula (10) or (11): where X represents O, CH 2 , C(=O), NR 11 , or CHR 35 and D represents a group represented by the following formula (6): where Q represents a single bond, NR 12 , or a group represented by the formula (13): and Y represents a group represented by the following formula (7) : where z represents a substitutable monocyclic or polycyclic aromatic ring; and B represents -NR 25 R 26 ; and R 1 to R 26 in the above formulae represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group.

Benzimidazole and pyridylimidazole derivatives

This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I The invention is particularly related to such compounds that bind with high selectivity and high affinity to the benzodiazepine site of GABAA receptors. This invention also relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in treatment of certain central nervous system (CNS) diseases. Novel processes for preparing compounds of Formula I are disclosed. This invention also relates to the use of benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds of Formula I in combination with one or more other CNS agents to potentiate the effects of the other CNS agents. Additionally this invention relates to the use such compounds as probes for the localization of GABAA receptors in tissue sections.