438618-59-8Relevant articles and documents
Normal and abnormal heme biosynthesis. 6. Synthesis and metabolism of a series of monovinylporphyrinogens related to harderoporphyrinogen. further insights into the oxidative decarboxylation of porphyrinogen substrates by coproporphyrinogen oxidase
Lash, Timothy D.,Mani, Ukti N.,Keck, Anna-Sigrid I. M.,Jones, Marjorie A.
, p. 3183 - 3192 (2010)
A series of vinylporphyrinogens were prepared to probe the enzyme coproporphyrinogen oxidase (CPO). Six (2-chloroethyl)porphyrins were synthesized from a common dipyrrylmethane via a,c-biladiene intermediates in excellent yields. Subsequent dehydrohalogen