439913-11-8

Basic information

• Product Name: Cyclopropanecarboxylic acid, 2-formyl-1-methyl-, ethyl ester, (1R,2R)- (9CI)
• Synonyms: Cyclopropanecarboxylic acid, 2-formyl-1-methyl-, ethyl ester, (1R,2R)- (9CI)
• CAS NO: 439913-11-8
• Molecular Formula: C8H12O3
• Molecular Weight: 156.17908
• Product Categories: CARBOXYLICESTER;ALDEHYDE
• Mol File: 439913-11-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarboxylic acid, 2-formyl-1-methyl-, ethyl ester, (1R,2R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 2-formyl-1-methyl-, ethyl ester, (1R,2R)- (9CI)(439913-11-8)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 2-formyl-1-methyl-, ethyl ester, (1R,2R)- (9CI)(439913-11-8)

Safety Data

• Hazardous Substances Data: 439913-11-8(Hazardous Substances Data)

Upstream product

• 258821-59-9 (1R,2R,1S')-1-ethoxycarbonyl-1-methyl-2-(1',2'-dihydroxyethyl)cyclopropane 

Downstream Products

• 439913-09-4 ethyl (1R,2R)-2-hydroxymethyl-1-methylcyclopropanecarboxylate 

Relevant articles and documents

Stereoselective synthesis of novel types of cyclopropyl carbocyclic nucleosides containing quaternary stereogenic centers

Versatile and stereocontrolled synthetic entries to novel types of cyclopropyl carbocyclic nucleosides are described. The target products have been synthesized from suitable cyclopropane precursors obtained, in turn, from olefinic compounds derived from D-glyceraldehyde as a chiral precursor. Selective manipulation of the functional groups has allowed the preparation of enantiopure nucleosides, some of them displaying opposite chirality. All these molecules contain a quaternary stereogenic carbon at C-1 or C-3 of the cyclopropane ring and bear an amino, a hydroxymethyl, or a methyl group as an additional substituent. In one instance, thymine is directly linked to the cyclopropane. A methylene unit serves as the spacer in the other synthesized nucleosides.