440124-25-4 Usage
General Description
3-Bromo-5-chloropyrazine-2-carbonitrile is a chemical compound with the molecular formula C5HBrClN3. 3-Bromo-5-chloropyrazine-2-carbonitrile is made up of multiple elements, including bromine, chlorine, carbon, nitrogen, and hydrogen. It belongs to the class of organic compounds known as pyrazines, which are polycyclic aromatic compounds containing a pyrazine ring, a six-membered aromatic heterocycle made up of two nitrogen atoms and four carbon atoms. It is used as a reagent in organic synthesis, and its properties may vary depending on factors such as temperature, pressure, concentration, and pH. It should be handled with care due to its potential reactiveness or toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 440124-25-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,1,2 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 440124-25:
(8*4)+(7*4)+(6*0)+(5*1)+(4*2)+(3*4)+(2*2)+(1*5)=94
94 % 10 = 4
So 440124-25-4 is a valid CAS Registry Number.
InChI:InChI=1/C5HBrClN3/c6-5-3(1-8)9-2-4(7)10-5/h2H
440124-25-4Relevant articles and documents
Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors
Ioannidis, Stephanos,Lamb, Michelle L.,Davies, Audrey M.,Almeida, Lynsie,Su, Mei,Bebernitz, Geraldine,Ye, Minwei,Bell, Kirsten,Alimzhanov, Marat,Zinda, Michael
scheme or table, p. 6524 - 6528 (2010/05/18)
The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.
Pyrimidine, pyrazine and triazine derivatives
-
, (2008/06/13)
The present invention is a pyrimidine, triazine or pyrazine derivative of the formula or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, R4, X, Y and Z are as defined in the specification. The invention is a pharmaceutical composition containing an effective amount of the compound of formula 1, its preparation and to a method of treatment, control or prevention of acute and/or chronic neurological disorders by administering a therapeutically effective amount of a compound of formula 1.
