441785-21-3 Usage
General Description
P-[[[1-[(6-AMINO-9H-PURIN-9-YL)METHYL]CYCLOPROPYL]OXY]METHYL]-PHOSPHONIC ACID, also known as PMEA, is a chemical compound with antiviral properties. PMEA is a nucleotide analog that inhibits the replication of certain viruses, including HIV and hepatitis B virus. It works by blocking the action of viral DNA polymerase, preventing the virus from making copies of its genetic material. PMEA has been investigated as a potential treatment for HIV and hepatitis B, and has shown promise in laboratory and animal studies. It is an important compound in the development of antiviral drugs and continues to be studied for its potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 441785-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,1,7,8 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 441785-21:
(8*4)+(7*4)+(6*1)+(5*7)+(4*8)+(3*5)+(2*2)+(1*1)=153
153 % 10 = 3
So 441785-21-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N5O4P/c11-8-7-9(13-4-12-8)15(5-14-7)3-10(1-2-10)19-6-20(16,17)18/h4-5H,1-3,6H2,(H2,11,12,13)(H2,16,17,18)
441785-21-3Relevant articles and documents
NUCLEOSIDE PHOSPHONATE DERIVATIVES USEFUL IN THE TREATMENT OF HIV INFECTIONS
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, (2008/06/13)
The present invention relates to a method of treating HIV infections by administering a nucleoside phosphonate derivative represented by formula (I).
