4437-01-8

Basic information

• Product Name: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER
• Synonyms: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER;Heptaetheylene glycol methyl ether;mPEG7;Methoxyheptaethylene glycol, Monomethoxy-PEG (n=7);MPEG7-OH;Heptaetheylene glycol MonoMethyl ether;2,5,8,11,14,17,20-Heptaoxadocosan-22-ol;3,6,9,12,15,18,21-heptaoxadocosan-1-ol
• CAS NO: 4437-01-8
• Molecular Formula: C₁₅H₃₂O₈
• Molecular Weight: 340.41
• Product Categories: Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols;Chemical Biology;Chemical Synthesis;High Oligomer Purity PEG;PEGylation
• Mol File: 4437-01-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 416 °C at 760 mmHg
• Flash Point: 205.4 °C
• Appearance: /
• Density: 1.09
• Vapor Pressure: 1.16E-08mmHg at 25°C
• Refractive Index: 1.4540-1.4580
• Storage Temp.: -20°C
• PKA: 14.36±0.10(Predicted)
• CAS DataBase Reference: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER(4437-01-8)
• EPA Substance Registry System: HEPTAETHYLENE GLYCOL MONOMETHYL ETHER(4437-01-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4437-01-8(Hazardous Substances Data)

Usage

Description

m-PEG7-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

InChI:InChI=1/C15H32O8/c1-17-4-5-19-8-9-21-12-13-23-15-14-22-11-10-20-7-6-18-3-2-16/h16H,2-15H2,1H3

Upstream product

• 112-60-7 Tetraethylene glycol 
• 52995-76-3 1-chloro-3,6,9-trioxadecane 

Downstream Products

• 79622-11-0 2,5,8,11,14,17,20-heptaoxadocosan-22-yl 4-methylbenzene-1-sulfonate 
• 170572-38-0 2,5,8,11,14,17,20-heptaoxadocosan-22-amine 
• 477775-58-9 6-{2-[2-(2-{2-[2-(2-Benzyloxyethoxy)ethoxy]ethoxy}-ethoxy)-ethoxy]-ethoxy}-hexanoic Acid Ethyl Ester 
• 75427-82-6 3-Benzyloxypropylenbis(3,6,9,12,15,18,21-heptaoxadocosanoat) 
• 287391-40-6 4-(2-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzaldehyde 
• 477775-57-8 20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane 

Relevant articles and documents

Quantification of grafted poly(ethylene glycol)-silanes on silicon by time-of-flight secondary ion mass spectrometry

Silicon grafted monodisperse poly(ethylene glycol) (PEG) silanes with various PEG chain lengths and mixtures of these were systematically analyzed with static time-of-flight secondary ion mass spectrometry (TOF-SIMS). The mass spectra show differences in the various relative signal intensities, an observation that was used to elucidate important aspects of the grafting process. The relationship between PEG-silane fragment ion abundances and Si+ ion abundances were used to (i) qualitatively describe layer thicknesses of grafted mixtures of PEG-silanes on silicon, (ii) construct a calibration curve from which PEG chain length (or molecular mass) can be determined and (iii) quantitatively determine surface mixture compositions of grafted monodisperse PEG-silanes of different chain lengths (3, 7 and 11 PEG units). The results suggest that discrimination does take place in the adsorption process. The PEG-silane with the shorter PEG chain is discriminated for mixtures containing PEG3-silane, whereas the PEG-silane with the longer PEG chain is discriminated in PEG7/PEG11-silane mixtures. The origin of this difference in adsorption behavior is not well understood. Aspects of the grafting process and the TOF-SIMS analyses are discussed. Copyrigh

Hydrophilic Lipids

The new triesters of glycerol 1-8 with different oligoethylene glycol carboxylic acids ("hydrophilic lipids") have been synthesized and their complexation with alkali and alkaline earth metal cations has been investigated.