444122-13-8

Basic information

• Product Name: Silane, (1,1-dimethylethyl)[[(1R)-4-iodo-3,5,5-trimethyl-3-cyclohexen-1-yl]oxy]di methyl-
• CAS NO: 444122-13-8
• Molecular Formula: C15H29IOSi
• Molecular Weight: 380.385
• Mol File: 444122-13-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)[[(1R)-4-iodo-3,5,5-trimethyl-3-cyclohexen-1-yl]oxy]di methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)[[(1R)-4-iodo-3,5,5-trimethyl-3-cyclohexen-1-yl]oxy]di methyl-(444122-13-8)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)[[(1R)-4-iodo-3,5,5-trimethyl-3-cyclohexen-1-yl]oxy]di methyl-(444122-13-8)

Safety Data

• Hazardous Substances Data: 444122-13-8(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 20548-02-1 (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one 
• 130583-95-8 (4R,6R)-4-[(tert-butyldimethylsilyl)oxy]-2,2,6-trimethylcyclohexan-1-one 
• 444122-12-7 [(4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-2,2,6-trimethyl-cyclohex-(Z)-ylidene]-hydrazine 

Downstream Products

• 83021-07-2 (S,E)-4-[4-(tert-butyldimethylsilyloxy)-2,6,6-trimethylcyclohex-1-en-1-yl]but-3-en-2-one 
• 472-70-8 (3R)-cryptoxanthin 
• 144-68-3 zeaxanthin 
• 444122-14-9 (S,E)-tert-butyldimethylsilyl 4-(but-1-en-3-yn-1-yl)-3,5,5-trimethylcyclohex-3-en-1-yl ether 
• 444122-16-1 (R)-4-((1E,3E)-4-iodo-3-methylbuta-1,3-dien-1-yl)-3,5,5-trimethylcyclohex-3-en-1-ol 
• 444122-15-0 (S)-4-[(E)-but-1-en-3-ynyl]-3,5,5-trimethylcyclohex-3-en-1-ol 
• 214335-71-4 (-)-[(S)-4-(tert-butyldimethylsilyloxy)-2,6,6-trimethylcyclohex-1-enyl]methanol 

Relevant articles and documents

Stereocontrolled synthesis and configurational assignment of (R)-all-trans-11,12-dihydro-3-hydroxyretinol

The synthesis of (R)-all-trans-11,12-dihydro-3-hydroxyretinol and putative metabolites of the side-chain functional group has been achieved in a stereocontrolled manner via the Suzuki-Hiyama cross-coupling reaction of an enantiopure (hydroxycyclohexenyl)alkenyliodide and non-conjugated pinacolboranedienoate, which allowed the absolute configuration of this natural product to be confirmed.

Total synthesis of peridinin and related C37-norcarotenoid butenolides

As an extension of our synthesis of symmetrical carotenoids, the preparation of the highly functionalized C37-norcarotenoid butenolide peridinin (1), its 6′-epi- and 11′Z stereoisomers has been completed. Featuring a central dihalogenated Csub