4443-56-5Relevant articles and documents
Consecutive approach to alkenes that combines radical addition of phosphorus hydrides with horner-wadsworth-emmons-type reactions
Healy, Mark P.,Parsons, Andrew F.,Rawlinson, James G. T.
, p. 1597 - 1600 (2007/10/03)
(Chemical Equation Presented) Addition of diethyl thiophosphite to terminal alkenes, in the presence of a radical initiator, followed by deprotonation of the phosphonothioate and reaction with a ketone, offers a concise one-pot approach to substituted alkenes. This novel method, which can incorporate alkylation or acylation steps, can be applied to the stereoselective formation of sterically hindered tri- and tetrasubstituted alkenes.
