4445-43-6

Basic information

• Product Name: 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID
• Synonyms: 2-Amino-4-phenylbenzoic acid
• CAS NO: 4445-43-6
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.24
• Product Categories: Carboxylic Acids;Carboxylic Acids;Fused Ring Systems
• Mol File: 4445-43-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 427°C at 760 mmHg
• Flash Point: 212°C
• Appearance: /
• Density: 1.257g/cm³
• Vapor Pressure: 4.75E-08mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID(4445-43-6)
• EPA Substance Registry System: 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID(4445-43-6)

Safety Data

• Hazardous Substances Data: 4445-43-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H11NO2/c14-12-8-10(6-7-11(12)13(15)16)9-4-2-1-3-5-9/h1-8H,14H2,(H,15,16)

Upstream product

• 99847-13-9 3-nitrobiphenyl-4-carboxylic acid 
• 109497-00-9 6-phenylindoline-2,3-dione 
• 800375-15-9 methyl 3-amino[1,1’-biphenyl]-4-carboxylate 
• 135484-83-2 2-amino-4-bromo-benzoic acid methyl ester 
• 158580-57-5 methyl 4-bromo-2-nitrobenzoate 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 98-80-6 phenylboronic acid 
• 99419-89-3 3-nitro-biphenyl-4-carbonitrile 
• 626-01-7 3-Iodoaniline 
• 63608-68-4 3-iodo-isonitrosoacetanilide 
• 20780-77-2 6-iodoisatin 

Downstream Products

• 100965-88-6 3-nitro-7-phenyl-quinolin-4-ol 
• 108618-34-4 3-amino-7-phenyl-quinolin-4-ol 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES

The invention relates to antibacterial compounds of formula I, wherein R1 is H or halogen; R2 is the group M; R3 is H or halogen; M is MA or MB wherein A is a bond or C≡C; R1A is H or halo

Biaryl substituted alkylboronate esters as thrombin inhibitors

Thrombin is a serine protease that plays an important role in the blood coagulation cascade, and is a target enzyme for new therapeutic agents. Ac- (D)-Phe-Pro-boroArg-OH (DuP 714) was found to be a highly effective thrombin inhibitor. In order to reduce the peptidic nature of DuP 714, we have designed a series of novel biaryl substituted alkylboronate esters as potent thrombin inhibitors. The most potent compounds have subnanomolar affinity for thrombin.