444665-25-2

Basic information

• Product Name: 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-ylquinolin-2(1H)-one
• CAS NO: 444665-25-2
• Molecular Weight: 483.825
• Mol File: 444665-25-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-ylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-ylquinolin-2(1H)-one(444665-25-2)
• EPA Substance Registry System: 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-ylquinolin-2(1H)-one(444665-25-2)

Safety Data

• Hazardous Substances Data: 444665-25-2(Hazardous Substances Data)

Upstream product

• 444665-23-0 tert-butyl 4-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydroquinolin-7-yl]-3,6-dihydropyridine-1(2 H)-carboxylate 
• 444663-58-5 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxy-2(1H)-quinolinone 
• 444663-59-6 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-2(1H)-quinolinone 
• 444663-44-9 t-butyl 3-(2,6-dibromo-4-methoxyphenyl)-propionate 
• 444663-45-0 3-(2,6-dibromo-4-methoxyphenyl)-propionic acid 
• 130445-13-5 1,3-dibromo-2-(bromomethyl)-5-methoxybenzene 
• 14542-71-3 2,6-dibromo-4-methoxytoluene 
• 444665-24-1 tert-Butyl 4-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydroquinolin-7-yl]piperidine-1-carboxylate 
• 527680-10-0 5-bromo-1-(2,6-dichloro-phenyl)-7-methoxy-1H-quinolin-2-one 
• 444663-46-1 N-(2,6-dichlorophenyl)-3-(2,6-dibromo-4-methoxyphenyl)-propionamide 
• 444663-43-8 5-bromo-1-(2,6-dichlorophenyl)-3,4-dihydro-7-methoxy-2(1H)-quinolinone 

Relevant articles and documents

p38 inhibitors: Piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and dihydroquinazolinones

We have synthesized a series of C7-piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and dihydroquinazolinones that are highly potent inhibitors of both p38 MAP kinase activity and TNF-α release. The 4-aminopentamethylpiperidin