451493-31-5 Usage
General Description
2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-methylbenzenesulfonate (1:2) is a complex chemical compound consisting of 2-propenamide, quinazolinyl, and 4-methylbenzenesulfonate. It is used as a potential antineoplastic agent for the treatment of cancer. 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-methylbenzenesulfonate (1:2) has been studied in relation to its therapeutic properties and has shown promise in inhibiting the growth of cancer cells. Its unique structure and composition make it a valuable subject for further research in the field of oncology and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 451493-31-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,1,4,9 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 451493-31:
(8*4)+(7*5)+(6*1)+(5*4)+(4*9)+(3*3)+(2*3)+(1*1)=145
145 % 10 = 5
So 451493-31-5 is a valid CAS Registry Number.
451493-31-5Relevant articles and documents
Quinazoline derivatives
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Page/Page column 45, (2010/02/07)
A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a superior tyrosine-specific protein kinase inhibitory activity and is useful as a pharmaceutical agent, particularly as an agent for the prophylaxis or treatment of various cancers, psoriasis or diseases caused by arteriosclerosis, and the like.