452-92-6

Basic information

• Product Name: 5-BROMO-2,4-DIFLUOROANILINE
• Synonyms: 5-BROMO-2,4-DIFLUOROANILINE;3-BROMO-4,6-DIFLUOROANILINE;2,4-DIFLUORO-5-BROMOANILINE;BUTTPARK 100\01-17;5-Bromo-2,4-difluoroaniline 99%;Benzenamine, 5-bromo-2,4-difluoro-;5-BROMO-2,4-DIFLUORO-PHENYLAMINE
• CAS NO: 452-92-6
• Molecular Formula: C₆H₄BrF₂N
• Molecular Weight: 208
• Product Categories: Other fluorin-contained compounds;Amines;C2 to C6;Nitrogen Compounds
• Mol File: 452-92-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 25-29 °C(lit.)
• Boiling Point: 223℃
• Flash Point: >230 °F
• Appearance: /
• Density: 1.788
• Storage Temp.: 2-8°C
• PKA: 2.19±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2,4-DIFLUOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2,4-DIFLUOROANILINE(452-92-6)
• EPA Substance Registry System: 5-BROMO-2,4-DIFLUOROANILINE(452-92-6)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 452-92-6(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Upstream product

• 348-57-2 2,4-difluorobromobenzene 
• 345-24-4 5-bromo-2,4-difluoronitrobenzene 

Downstream Products

• 357647-44-0 3H-imidazole-4-carboxylic acid (5-bromo-2,4-difluoro-phenyl)-amide 
• 643746-85-4 benzyl 5-bromo-2,4-difluorophenylcarbamate 
• 2375840-87-0 methyl 3-chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate 
• 398-93-6 N-(5-bromo-2,4-difluorophenyl)acetamide 
• 1016234-82-4 (-)-(cis)-7-bromo-8-fluoro-1,3,4,14b-tetrahydro-2H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepin-1-amine (4S)-2-hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinane 2-oxide (1:1) 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

Indole compound as well as preparation method, pharmaceutical composition and application thereof

The invention discloses an indole compound as well as a preparation method, a pharmaceutical composition and an application thereof. Specifically, the invention relates to an indole derivative as shown in a general formula I and a medicinal salt thereof, a preparation method of the indole derivative, a composition containing one or more compounds, and applications of the compounds in preparation of medicines for preventing and/or treating diseases related to IDO1 and/or TDO.

SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF

This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compounds of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.