452307-59-4Relevant articles and documents
De novo design, synthesis, and evaluation of novel nonsteroidal phenanthrene ligands for the estrogen receptor
Schmidt, Jonathan M.,Mercure, Julie,Tremblay, Gilles B.,Pagé, Martine,Kalbakji, Aida,Feher, Miklos,Dunn-Dufault, Robert,Peter, Markus G.,Redden, Peter R.
, p. 1408 - 1418 (2007/10/03)
Although there are many estrogen receptor antagonists with improved tissue selectivity profiles compared with tamoxifen, optimal tissue selectivity has not yet been demonstrated. As such there is still a need for additional diversity and new chemical scaf