452339-73-0Relevant articles and documents
Preparation method and application of polyoxometalate crystal
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Paragraph 0014-0015, (2017/08/31)
The invention belongs to the technical field of organocatalysis and in particular relates to a preparation method and application of a polyoxometalate crystal. The preparation method disclosed by the invention comprises the following steps: by taking Na2WO4.2H2O, NaVO3.2H2O, disodium hydrogen phosphate, manganese acetate and benzyl tri-n-butylammonium chloride as raw materials, preparing the heteropolyacid crystal. Catalyzed preparation of an anti-asthma drug vilanterol trifenatate intermediate is realized by taking the polyoxometalate crystal as a catalyst. The defect in the conventional process that a strong base is adopted is overcome, the pressure for environmental protection is alleviated, the process route is green and environment-friendly, and the requirements on the conventional industrial production are met.
PROCESS FOR THE PREPARATION OF VILANTEROL AND INTERMEDIATES THEREOF
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Paragraph 0133; 0134, (2015/09/23)
An improved process for the preparation of vilanterol and pharmaceutically acceptable salts thereof is disclosed. More specifically the improved process for preparing intermediates for the preparation of vilanterol is disclosed.
PHENETHANOLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISEASES
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Page 43-44, (2010/02/06)
The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.