4532-96-1

Basic information

• Product Name: 1-Isopropylimidazole
• Synonyms: 1-Isopropyl-1H-imidazole;1-Isopropylimidazole;1-(propan-2-yl)-1H-iMidazole;1-(1-methylethyl)-1H-Imidazole
• CAS NO: 4532-96-1
• Molecular Formula: C₆H₁₀N₂
• Molecular Weight: 110.16
• EINECS: 1312995-182-4
• Mol File: 4532-96-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 104°C/7mmHg(lit.)
• Flash Point: 76.7 °C
• Appearance: light yellow or colorless transparent liquid
• Density: 0.96 g/cm³
• Refractive Index: 1.4800 to 1.4840
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.15±0.20(Predicted)
• CAS DataBase Reference: 1-Isopropylimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Isopropylimidazole(4532-96-1)
• EPA Substance Registry System: 1-Isopropylimidazole(4532-96-1)

Safety Data

• Hazardous Substances Data: 4532-96-1(Hazardous Substances Data)

Usage

General Description

1-Isopropylimidazole, also known as 1-(1-methylethyl)-1H-imidazole, is a chemical compound with the molecular formula C6H10N2. It is an imidazole derivative that is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. With its high stability and reactivity, 1-Isopropylimidazole is used as a catalyst in polymerization reactions and as a reagent in the synthesis of pharmaceuticals, agrochemicals, dyes, and other specialty chemicals. It is also used as an intermediate in the production of corrosion inhibitors, surfactants, and lubricants, making it a versatile and valuable compound in the chemical industry. Additionally, it has applications in electroplating, metal finishing, and as a corrosion inhibitor in cooling water systems.

Upstream product

• 288-32-4 1H-imidazole 
• 75-26-3 isopropyl bromide 
• 75-31-0 isopropylamine 
• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 75-30-9 2-iodo-propane 

Downstream Products

• 938051-33-3 1-benzyl-3-isopropylimidazolium bromide 
• 1207863-91-9 1-isopropyl-3-[(2-methoxyphenyl)aminocarbonylmethyl]imidazolium chloride 
• 1191914-75-6 3-(3,5-di-tert-butyl-2-hydroxyphenyl)-1-isopropyl-1H-imidazol-3-ium bromide 
• 398460-83-8 1,3-diisopropylimidazolium iodide 

Relevant articles and documents

Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

A novel approach towards the synthesis of radiolabeled organometallic rhenium complexes is presented. We successfully synthesized and analyzed the first 188Re-labeled N-heterocyclic biscarbene complex, trans-dioxobis(1,1′-methylene-bis(3,3′-diisopropylimidazolium-2- ylidene))188rhenium(V) hexafluorophosphate (188Re-4) via transmetalation using an air-stable and moisture-stable silver(I) biscarbene complex. In order to assess the viability of this complex as a potential lead structure for in vivo applications, the stability of the 188Re-NHC complex was tested in physiologically relevant media. Ultimately, our studies illustrate that the complex we synthesized dissociates rapidly and is therefore unsuitable for use in radiopharmaceuticals. However, it is clear that the transmetalation approach we have developed is a rapid, robust, and mild method for the synthesis of new 188Re-labeled carbene complexes. Copyright

Synthesis, crystal structures and blue emission of zinc(II) halide complexes of 1-alkyl-imidazole and (-)-nicotine

Zn(II) halide complexes of the form L2ZnX2 (X =Cl, Br, I) containing bio-relevant or bio-related ligands like 1-alkyl-imidazoles (alkyl=methyl, ethyl and iso-propyl) or (-)-nicotine are presented. All complexes were characterized by 1H NMR spectroscopy, mass spectrometry and elemental analysis. The molecular structures of the majority of complexes were determined by single crystal X-ray diffraction. The zinc ion exists in a tetrahedral environment coordinated by two halide anions and two nitrogen atoms of the N-heterocycles. Upon photoexcitation the nicotine complexes feature a blue emission which we tentatively assign to phosphorescence.

Process for the preparation of 1-hexene and 1-oxtene

The present invention relates to a manufacturing method of 1-hexene and 1-octene from an olefin under the presence of a catalyst composition. The catalyst composition comprises: at least one type of an organic ligand compound selected from the group consisting of a compound represented by chemical formula 1, a compound represented by chemical formula 2, and a compound represented by chemical formula 3; at least one type of transition metal or a transition metal precursor selected from the group consisting of group IV to group XII elements; and a promotor. The manufacturing method of the present invention reduces generation of byproducts, and can manufacture 1-hexene and 1-octene from an olefin with high selectivity and reaction activity.