457060-45-6Relevant articles and documents
Nucleophilic Isomerization of Epoxides by Pincer-Rhodium Catalysts: Activity Increase and Mechanistic Insights
Tian, Yingying,Jürgens, Eva,Mill, Katharina,Jordan, Ronja,Maulbetsch, Theo,Kunz, Doris
, p. 4028 - 4035 (2019/06/25)
Herein, we present the efficient isomerization of epoxides into methyl ketones with a novel pincer-rhodium complex under very mild conditions. The catalyst system has an excellent functional group tolerance and a wide array of epoxides was tested. The corresponding methyl ketones were obtained in very high yields with excellent chemo- and regioselectivity. In addition, we investigated mechanistic details like the isomerization of the catalyst, and we obtained evidence that the catalytic cycle follows a β-hydride elimination-reductive elimination pathway after the nucleophilic ring opening of the epoxide.
An unexpected oxidation of unactivated methylene C-H using DIB/TBHP protocol
Zhao, Yi,Yim, Wai-Leung,Tan, Chong Kiat,Yeung, Ying-Yeung
supporting information; experimental part, p. 4308 - 4311 (2011/10/08)
An in situ generated hypervalent iodine species, bis(tert-butylperoxy) iodobenzene, was used as a peroxy radical source for the oxidation of unreactive, remote, and isolated alkyl (cyclic or aliphatic) esters and amides to the corresponding keto compounds under very mild conditions.
