4626-45-3

Basic information

• Product Name: 2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester
• CAS NO: 4626-45-3
• Molecular Formula: C19H17NO8
• Molecular Weight: 387.346
• Mol File: 4626-45-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester(4626-45-3)
• EPA Substance Registry System: 2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester(4626-45-3)

Safety Data

• Hazardous Substances Data: 4626-45-3(Hazardous Substances Data)

Usage

General Description

2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester is a chemical compound with the molecular formula C21H19NO8. It is a tetramethyl ester derivative of 2,3,4,5-Pyridinetetracarboxylic acid, which is a pyridine derivative. 2,3,4,5-Pyridinetetracarboxylic acid, 6-phenyl-, tetramethyl ester is used in organic synthesis and as a building block for the synthesis of various organic compounds. It has potential applications in pharmaceutical and agrochemical industries, as well as in materials science. It is important to handle this compound with care and follow safety guidelines due to its potential hazardous properties.

Upstream product

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• 224640-32-8 1-methyl-2-phenyl-4,5-bis(methyl-4-tolylamino)-1H-imidazole 
• 224641-03-6 1-methyl-2,3-bis(methyl-4-tolylamino)-9-phenyl-1,9-dihydroimidazo<1,2-a>pyridine-5,6,7,8-tetracarboxylic acid-tetramethyl ester 
• 883-34-1 3-methyl-5-phenylimidazo<5,1-b>thiazole 

Relevant articles and documents

Reduction of 4H-imidazoles - Synthesis and reactivity of 4,5- diaminoimidazoles bearing a tetra-aminoethene substructure

The 4H-imidazoles (1) can be reduced after deprotonation to the trianion (4) by two consecutive single electron transfer reactions. Subsequent quenching by simple electrophiles constitutes a convenient route to the title substances of type (5). The unexpected regioselectivity towards bielectrophilic building blocks facilitates the synthesis of highly substituted heterospiranes (7) and the imidazo crown ethers (8). The trianion (4) reacted with two molecules of CS2 at the exocyclic nitrogen atoms exclusively to afford after quenching the dithiocarbamates (10) and the cyclic thiuram sulfides (11). The new imidazole derivatives of type (5) showed only slight electron donor properties. An electrophilic attack led with preference to a quarternization of the unsubstituted ring nitrogen atom of 5, as shown by the synthesis of compound (13). A similar behaviour was observed by treatment of 5 with acetylenedicarboxylate, in which the red 1:2 adduct (14) was formed in yields up to 76 %.

Studies on Heteropentalenes. V. Cycloadditions of 5-Aryl-3-methylimidazothiazoles with Acetylenic Esters Leading to 5-Aryl-3-methylthiazolobenzimidazoles and Related Heterocycles

Cycloaddition of 5-aryl-3-methylimidazothiazoles with dialkyl acetylenedicarboxylate in an aprotic nonpolar solvent gives a number of products including epimeric thiazolobenzimidazoles (3 and 4) , epimeric 5,10b-ethenothiaz