464-74-4

Basic information

• Product Name: arenobufagin
• Synonyms: arenobufagin;3β,11α,14-Trihydroxy-12-oxo-5β-bufa-20,22-dienolide;(3beta,5beta,11alpha)-3,11,14-Trihydroxy-12-oxobufa-20,22-dienolide;Arenobufogenin
• CAS NO: 464-74-4
• Molecular Formula: C₂₄H₃₂O₆
• Molecular Weight: 416.511
• Mol File: 464-74-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 222-228℃
• Boiling Point: 637.2°Cat760mmHg
• Flash Point: 219.3°C
• Appearance: /
• Density: 1.349
• Vapor Pressure: 6.4E-19mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• PKA: 12.39±0.70(Predicted)
• CAS DataBase Reference: arenobufagin(CAS DataBase Reference)
• NIST Chemistry Reference: arenobufagin(464-74-4)
• EPA Substance Registry System: arenobufagin(464-74-4)

Safety Data

• Hazardous Substances Data: 464-74-4(Hazardous Substances Data)

Usage

General Description

Arenobufagin is a chemical compound found in the skin of toads, particularly members of the Bufo genus. It is an active ingredient in traditional Chinese medicine and has been investigated for its potential medicinal properties, including anti-cancer and heart-strengthening effects. Arenobufagin has been found to inhibit the growth of various cancer cell lines and induce apoptosis, making it a subject of interest for cancer research. It also has potential as a treatment for heart failure and other cardiovascular conditions due to its ability to enhance cardiac contractility. However, it is important to note that arenobufagin is toxic in high doses and should be used with caution and under the supervision of a qualified healthcare professional.

InChI:InChI=1/C24H32O6/c1-22-9-7-15(25)11-14(22)4-5-17-19(22)20(27)21(28)23(2)16(8-10-24(17,23)29)13-3-6-18(26)30-12-13/h3,6,12,14-17,19-20,25,27,29H,4-5,7-11H2,1-2H3/t14-,15+,16-,17?,19?,20+,22+,23+,24+/m1/s1