4663-99-4

Basic information

• Product Name: pyridine-3,5-dicarboxamide
• CAS NO: 4663-99-4
• Molecular Formula: C₇H₇N₃O₂
• Molecular Weight: 165.1494
• Mol File: 4663-99-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 479.5°C at 760 mmHg
• Flash Point: 243.8°C
• Density: 1.375g/cm³
• Vapor Pressure: 2.34E-09mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: pyridine-3,5-dicarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: pyridine-3,5-dicarboxamide(4663-99-4)
• EPA Substance Registry System: pyridine-3,5-dicarboxamide(4663-99-4)

Safety Data

• Hazardous Substances Data: 4663-99-4(Hazardous Substances Data)

Usage

General Description

Pyridine-3,5-dicarboxamide, also known as nicotinamide, is a derivative of vitamin B3 and is an important nutrient for the human body. It plays a crucial role in the production of energy and can also act as an antioxidant, helping to protect cells from damage caused by harmful molecules. Nicotinamide is frequently used in various skin care products for its ability to improve the appearance of aging skin, reduce hyperpigmentation, and promote overall skin health. Additionally, as a precursor to the coenzymes NAD+ and NADP+, nicotinamide is involved in numerous metabolic processes and has been studied for its potential therapeutic effects in treating conditions such as diabetes, arthritis, and even Alzheimer's disease. Its diverse range of applications make it an essential compound in the field of biochemistry and medicine.

Upstream product

• 499-81-0 3,5-Pyridinedicarboxylic acid 
• 4591-55-3 dimethyl pyridine-3,5-dicarboxylate 
• 15074-61-0 pyridine-3,5-dicarbonyl dichloride 

Downstream Products

• 4318-78-9 3,5-diaminopyridine 
• 106473-05-6 4-cyano-1-(2,6-dichloro-benzyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diamide 
• 107920-49-0 1-(2,6-dichloro-benzyl)-1,2-dihydro-pyridine-3,5-dicarboxylic acid diamide 
• 107921-65-3 1-(2,6-dichlorobenzyl)-1,4-dihydropyridine-3,5-dicarboxamide 
• 1195-58-0 pyridine-3,5-dicarbonitrile 
• 97031-68-0 3,5-dicarbamoyl-1-(2,6-dichlorobenzyl)pyridinium bromide 

Relevant articles and documents

Structure of the dimers arising from one-electron electrochemical reduction of pyridinium salts 3,5-disubstituted with electron-withdrawing groups

One-electron electrochemical reduction of the salts 1-benzyl-3,5-bis(methylcarbamoyl)pyridinium bromide 3a and 1-benzyl-3,5-dicarbamoylpyridinium bromide 3b yields mixtures of four isomeric dimers, as shown by HPLC analysis and mass spectrometry. 1/

Efficient synthesis of 3,5-dicarbamoyl-1,4-dihydropyridines from pyridinium salts: Key molecules in understanding NAD(P)+/NAD(P)H pathways

3,5-Dicarbamoyl-1,4-dihydropyridines were prepared in high yields using a green protocol by reduction of the corresponding pyridinium salts in aqueous buffered sodium dithionite solutions. The pH value is a fundamental parameter for the reduction step and depends on the nature of substituent groups at positions 1, 3, and 5 of the pyridinium salts. These 3,5-dicarbamoyl dihydropyridines show a lower tendency towards oxidation and a higher stability than N-benzyl-3-carbamoyl-1,4-dihydropyridine at low pH values.

ANIONS AND DERIVED SALTS WITH HIGH DISSOCIATION IN NON-PROTOGENIC SOLVENTS

Salts with formula X-M+ wherein M+ is Li, Na, K, an ammonium, a phosphonium, an imidazolium, a pyridinium, or a pyrazolium and X- is an anion formed from covalent linking of two negative moieties to a positive onium-type core are provided. Also provided are electrolytes and batteries produced from these salts.