470463-36-6 Usage
General Description
N-(5-IODO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE is a chemical compound with the molecular formula C12H14IN2O. Its name indicates its structural characteristics: an iodine atom attached to a pyridin ring that is further attached to a propionamide group, while the propionamide itself has two methyl groups on its middle carbon. It's used primarily in the field of pharmaceuticals and scientific research for the synthesis of other complex chemical compounds. This chemical typically comes as a solid and it's highly advised to be handled and stored carefully, adhering strictly to safety measures. Specific physical and chemical properties, like melting or boiling points, may vary depending on factors such as pressure and temperature.
Check Digit Verification of cas no
The CAS Registry Mumber 470463-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,0,4,6 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 470463-36:
(8*4)+(7*7)+(6*0)+(5*4)+(4*6)+(3*3)+(2*3)+(1*6)=146
146 % 10 = 6
So 470463-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H13IN2O/c1-10(2,3)9(14)13-8-5-4-7(11)6-12-8/h4-6H,1-3H3,(H,12,13,14)
470463-36-6Relevant articles and documents
Rhodium(III)-catalyzed oxidative olefination of pyridines and quinolines: Multigram-scale synthesis of naphthyridinones
Zhou, Jun,Li, Bo,Hu, Fang,Shi, Bing-Feng
supporting information, p. 3460 - 3463 (2013/07/26)
A Rh(III)-catalyzed oxidative olefination of pyridines and quinolines has been achieved. This method has a broad substrate scope and has been applied to the expeditious, multigram-scale synthesis of naphthyridinones.
ETHYNYL COMPOUNDS USEFUL FOR TREATMENT OF CNS DISORDERS
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Page/Page column 34, (2011/07/06)
The present invention relates to ethynyl compounds of formula wherein X, Y, Z, and R4 are as defined herein or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. Compounds of formula I are positive allosteric modulators (PAM) of the metabotropic glutamate receptor subtype 5 (mGluR5) and they are therefore useful for the treatment of diseases related to this receptor.
