4712-11-2Relevant articles and documents
Preparation method of vitamin D2
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Paragraph 0089; 0091; 0100-0102; 0108; 0117-0119; 0125; 0134, (2021/05/12)
The invention belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of vitamin D2. Compared with the prior art, the method has the following beneficial effects: the invention provides a technical scheme for synthesizing vitamin D2 through photochemical reaction, thermal isomerization reaction, esterification reaction and saponification reaction by taking ergosterol as an initial raw material, and according to the technical scheme, the effect of high yield of the vitamin D2 is achieved by comprehensively optimizing an organic solvent system in which photochemical reaction is carried out and the temperature of thermal isomerization reaction and washing a saponification product by adopting a proper washing solution.