473528-55-1

Basic information

• Product Name: 8-(2-bromo-pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• Synonyms: 8-(2-bromo-pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• CAS NO: 473528-55-1
• Molecular Weight: 401.306
• Mol File: 473528-55-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-(2-bromo-pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(2-bromo-pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one(473528-55-1)
• EPA Substance Registry System: 8-(2-bromo-pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one(473528-55-1)

Safety Data

• Hazardous Substances Data: 473528-55-1(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 128071-75-0 2-bromopyridine-3-carboxaldehyde 
• 1021-25-6 1-Phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 

Relevant articles and documents

1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF ORL-1 RECEPTOR MEDIATED DISORDERS

The present invention is directed to novel 1,3,8-triazaspiro[4.5]decan-4-one derivatives of the general formulawherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.