473577-25-2

Basic information

• Product Name: (Z)-N-(1-deoxy-2,3:4,5-di-O-isopropylidene-D-xylo-1-ylidene)benzylamine-N-oxide
• CAS NO: 473577-25-2
• Molecular Weight: 335.4
• Mol File: 473577-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-N-(1-deoxy-2,3:4,5-di-O-isopropylidene-D-xylo-1-ylidene)benzylamine-N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-(1-deoxy-2,3:4,5-di-O-isopropylidene-D-xylo-1-ylidene)benzylamine-N-oxide(473577-25-2)
• EPA Substance Registry System: (Z)-N-(1-deoxy-2,3:4,5-di-O-isopropylidene-D-xylo-1-ylidene)benzylamine-N-oxide(473577-25-2)

Safety Data

• Hazardous Substances Data: 473577-25-2(Hazardous Substances Data)

Upstream product

• 13039-94-6 2,3,4,5-di-O-isopropylidene-D-xylose aldehyde 
• 622-30-0 N-benzyl hydroxylalmine 
• 473530-37-9 (4S,5R,4'R)-5-(Bis-isopropylsulfanyl-methyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 473530-36-8 D-xylose diisopropyldithioacetal 
• 532-20-7 D-xylofuranose 

Relevant articles and documents

New chiral nitrones in the synthesis of modified nucleosides

New chiral nitrones 7 and 12, easily prepared from D-xylose by multistep synthetic routes, undergo regioselective 1,3-dipolar cycloadditions with N-vinylated bases (uracil, adenine) giving isoxazolidinyl nucleosides in good yields. Attack of the dipolarophile on the Z-configuration of the nitrone through exo and endo transition states from the si face of nitrone (C-1′/C-3 erythro) affords C-3/C-5 cis (exo) and C-3/C-5 trans (endo) isoxazolidines as two major isomers.