473733-18-5 Usage
General Description
The chemical (1R)-1-(3-fluorophenyl)-2-methylpropylamine, also known as fluorenol, is a chiral amine that is commonly used in the synthesis of pharmaceuticals and fine chemicals. It is classified as a primary amine and contains a stereocenter at the alpha carbon, making it optically active. (1R)-1-(3-fluorophenyl)-2-methylpropylamine is often utilized as a chiral building block in the preparation of various drug molecules due to its ability to impart specific stereochemical characteristics. Additionally, (1R)-1-(3-fluorophenyl)-2-methylpropylamine has been studied for its potential applications in the treatment of neurological disorders and as a precursor in the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 473733-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,3,7,3 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 473733-18:
(8*4)+(7*7)+(6*3)+(5*7)+(4*3)+(3*3)+(2*1)+(1*8)=165
165 % 10 = 5
So 473733-18-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14FN/c1-7(2)10(12)8-4-3-5-9(11)6-8/h3-7,10H,12H2,1-2H3/t10-/m1/s1
473733-18-5Relevant articles and documents
THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS
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Page 267, (2008/06/13)
Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
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Page 143, (2008/06/13)
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
