475060-21-0 Usage
General Description
2-Acetamido-5-fluoro-4-picoline is a chemical compound that belongs to the category of organic substances. It features a fluoro group, a picoline group and an acetamido group in its molecular structure, indicating potential applications in various chemical reactions due to the presence of these functional groups. This chemical's molecular weight is 178.2 g/mol. Its empirical formula is C8H9FN2O. Further details such as specific physical properties, toxicity, and reactivity would need to be evaluated or researched in the context of specific tasks or applications. Due to its complex molecular structure, it can be used in the synthesis of various types of pharmaceuticals and complicated organic compounds. Its handling and storage should follow the standards for hazardous materials.
Check Digit Verification of cas no
The CAS Registry Mumber 475060-21-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,0,6 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 475060-21:
(8*4)+(7*7)+(6*5)+(5*0)+(4*6)+(3*0)+(2*2)+(1*1)=140
140 % 10 = 0
So 475060-21-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9FN2O/c1-5-3-8(11-6(2)12)10-4-7(5)9/h3-4H,1-2H3,(H,10,11,12)
475060-21-0Relevant articles and documents
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety
Nakayama, Kiyoshi,Kuru, Noriko,Ohtsuka, Masami,Yokomizo, Yoshihiro,Sakamoto, Atsunobu,Kawato, Haruko,Yoshida, Ken-Ichi,Ohta, Toshiharu,Hoshino, Kazuki,Akimoto, Katsuya,Itoh, Junko,Ishida, Hiroko,Cho, Aesop,Palme, Monica H.,Zhang, Jason Z.,Lee, Ving J.,Watkins, William J.
, p. 2493 - 2497 (2007/10/03)
Exchange of the ethylene tether in a series of pyridopyrimidine-based MexAB-OprM specific efflux pump inhibitors to an amide bond stabilized the olefin of the acrylic acid moiety, preventing facile photoisomerization to the Z-isomer. Furthermore, the activity was drastically improved in the amide tether variants, providing extremely potent acrylic acid and vinyl tetrazole analogues.
