478511-16-9

Basic information

• Product Name: [5'-13C]URIDINE
• Synonyms: [5'-13C]URIDINE
• CAS NO: 478511-16-9
• Molecular Formula: C9H12N2O6
• Molecular Weight: 245.21
• Mol File: 478511-16-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 514.6 °C at 760 mmHg
• Flash Point: 265 °C
• Appearance: /
• Density: 1.36 g/cm³
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: [5'-13C]URIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: [5'-13C]URIDINE(478511-16-9)
• EPA Substance Registry System: [5'-13C]URIDINE(478511-16-9)

Safety Data

• Hazardous Substances Data: 478511-16-9(Hazardous Substances Data)

Usage

Description

[5'-13C]URIDINE is a labeled nucleoside, specifically uridine, which is one of the four basic components of ribonucleic acid (RNA). It is a stable isotope-labeled compound where the carbon atom at the 5' position is replaced with a 13C isotope. This modification allows for the study of uridine's role in various biological processes and its interactions with other molecules.

Uses

Used in Research and Development:
[5'-13C]URIDINE is used as a research tool for studying the synthesis, metabolism, and function of RNA in biological systems. The stable isotope labeling enables researchers to track and analyze the behavior of uridine in cellular processes, such as transcription and translation, using techniques like mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy.
Used in Pharmaceutical Industry:
[5'-13C]URIDINE is used as a tracer compound in the development of new drugs targeting RNA-related diseases. The stable isotope labeling allows for the investigation of drug interactions with RNA and the study of the drug's mechanism of action at the molecular level.
Used in Diagnostic Applications:
[5'-13C]URIDINE can be employed as a diagnostic agent for detecting and monitoring RNA-related disorders. The stable isotope labeling provides a means to differentiate between normal and diseased states by analyzing the uptake, distribution, and metabolism of the labeled uridine in the body.
Used in Metabolic Studies:
[5'-13C]URIDINE is used as a metabolic tracer in the study of RNA turnover and synthesis in various organisms. The stable isotope labeling allows researchers to measure the rate of RNA synthesis and degradation, providing insights into the regulation of gene expression and the role of RNA in cellular processes.
Used in Biochemical Education:
[5'-13C]URIDINE can be utilized as an educational tool for teaching students about the structure, function, and metabolism of RNA in biological systems. The stable isotope labeling provides a hands-on experience for students to learn about the techniques used in studying RNA, such as mass spectrometry and NMR spectroscopy.