478529-49-6

Basic information

• Product Name: D-[4,5,6,6'-2H4]GLUCOSE
• Synonyms: D-[4,5,6,6'-2H4]GLUCOSE;D-Glucose-4,5,6,6'-d4;WQZGKKKJIJFFOK-GCGANLBKSA-N
• CAS NO: 478529-49-6
• Molecular Formula: C6H8D4O6
• Molecular Weight: 184.18
• Product Categories: Heterocycles, Carbohydrates & Derivatives, Diagnostic, Isotope Labelled Compounds
• Mol File: 478529-49-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: D-[4,5,6,6'-2H4]GLUCOSE(CAS DataBase Reference)
• NIST Chemistry Reference: D-[4,5,6,6'-2H4]GLUCOSE(478529-49-6)
• EPA Substance Registry System: D-[4,5,6,6'-2H4]GLUCOSE(478529-49-6)

Safety Data

• Hazardous Substances Data: 478529-49-6(Hazardous Substances Data)

Usage

Description

D-[4,5,6,6'-2H4]GLUCOSE, also known as D-Glucose-4,5,6,6'-d4, is a deuterated monosaccharide that is present in plants. It may exist in an open chain or cyclic conformation when in solution. This simple sugar plays a crucial role in photosynthesis and provides the energy required for cellular respiration.

Uses

Used in Metabolic Processes:
D-[4,5,6,6'-2H4]GLUCOSE is used as a substrate in various enzymic synthesis processes, such as the production of cyclohexyl-α and β-D-glucosides. Its deuterated nature allows for the study of metabolic pathways and enzyme mechanisms without interference from the natural abundance of glucose.
Used in Diagnostic Applications:
D-[4,5,6,6'-2H4]GLUCOSE serves as a diagnostic tool in the detection and monitoring of type 2 diabetes mellitus. By analyzing blood-glucose levels, healthcare professionals can assess an individual's glucose metabolism and manage their diabetes more effectively.
Used in Research and Development:
In the field of research, D-[4,5,6,6'-2H4]GLUCOSE is utilized to study the mechanisms of glucose transport and metabolism. Its deuterated form provides a unique tool for investigating glucose-related diseases, such as type 1 diabetes mellitus and potentially Huntington's disease, by analyzing blood-glucose levels and their impact on cellular functions.
Used in Pharmaceutical Industry:
D-[4,5,6,6'-2H4]GLUCOSE can be employed in the development of new drugs and therapies targeting glucose metabolism disorders. Its deuterated structure allows for the investigation of drug interactions with glucose metabolism pathways, potentially leading to the discovery of novel treatments for diabetes and other related conditions.
Used in Food and Beverage Industry:
In the food and beverage industry, D-[4,5,6,6'-2H4]GLUCOSE can be used as a non-nutritive sweetener or as a tracer to study the effects of glucose on taste perception and consumer preferences. Its deuterated form ensures that it does not contribute to the caloric content of food products while still providing valuable insights into glucose-related taste sensations.