479073-82-0

Basic information

• Product Name: Hydroxythiohomosildenafil
• Synonyms: Hydroxythiohomosildenafil;4-[[3-(4,7-Dihydro-1-Methyl-3-propyl-7-thioxo-1H-pyrazolo[4,3-d]pyriMidin-5-yl)-4-ethoxypheny;5-[2-Ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidine-7-thione
• CAS NO: 479073-82-0
• Molecular Formula: C23H32N6O4S2
• Molecular Weight: 520.66798
• Product Categories: Aromatics;Drug Analogues;Heterocycles;Sulfur & Selenium Compounds
• Mol File: 479073-82-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 174-177°C
• Boiling Point: 733.3±70.0 °C(Predicted)
• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 14.96±0.10(Predicted)
• CAS DataBase Reference: Hydroxythiohomosildenafil(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxythiohomosildenafil(479073-82-0)
• EPA Substance Registry System: Hydroxythiohomosildenafil(479073-82-0)

Safety Data

• Hazardous Substances Data: 479073-82-0(Hazardous Substances Data)

Usage

Description

Hydroxythiohomosildenafil, also known as a Sildenafil thiono analog, is a novel pyrazolopyrimidinethione with phosphodiesterase type 5 (PDE5) inhibiting properties. It is characterized by its pale yellow solid appearance and has potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
Hydroxythiohomosildenafil is used as a PDE5 inhibitor for the treatment of erectile dysfunction and other related conditions. Its ability to inhibit PDE5 leads to increased levels of cyclic guanosine monophosphate (cGMP), which in turn promotes vasodilation and enhances blood flow.
Used in Research and Development:
In the field of scientific research, Hydroxythiohomosildenafil serves as a valuable compound for studying the effects of PDE5 inhibition on various physiological processes. It can be used to develop new therapeutic strategies and explore the potential of PDE5 inhibitors in treating other medical conditions.
Used in Drug Delivery Systems:
Similar to gallotannin, Hydroxythiohomosildenafil can also benefit from novel drug delivery systems to enhance its efficacy and bioavailability. By employing various organic and metallic nanoparticles as carriers, the delivery, absorption, and therapeutic outcomes of Hydroxythiohomosildenafil can be improved, making it a more effective treatment option for patients.