480425-35-2

Basic information

• Product Name: 3-Methoxycarbonylphenylboronic acid pinacol ester
• Synonyms: METHYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE;3-METHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER;3-carbomethoxyphenylboronic acid pinacol ester;3-Carbomethoxyphenylboronic acid pinacol ester, Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate;Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate,97%;Methyl 3-((4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)Methyl)benzoate;3-(Methoxycarbonyl)benzeneboronic acid, pinacol ester;3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester
• CAS NO: 480425-35-2
• Molecular Formula: C₁₄H₁₉BO₄
• Molecular Weight: 262.11
• Product Categories: Acids and Derivatives;Boron, Nitrile, Thio,& TM-Cpds;Imidazoles ,Homopiperidines
• Mol File: 480425-35-2.mol
• Article Data: 36

Chemical Properties

• Melting Point: 91-95 °C(lit.)
• Boiling Point: 364.3 °C at 760 mmHg
• Flash Point: 174.1 °C
• Appearance: white crystalline powder
• Density: 1.08 g/cm³
• Vapor Pressure: 1.7E-05mmHg at 25°C
• Refractive Index: 1.498
• Storage Temp.: Refrigerator (+4°C)
• Water Solubility: Insoluble
• CAS DataBase Reference: 3-Methoxycarbonylphenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxycarbonylphenylboronic acid pinacol ester(480425-35-2)
• EPA Substance Registry System: 3-Methoxycarbonylphenylboronic acid pinacol ester(480425-35-2)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 480425-35-2(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

3-Methoxycarbonylphenylboronic Acid Pinacol Ester is used in the preparation of non-noviosylated coumermycin A1 analogs targeting heat shock protein 90 dimer with dimeric inhibitors.

InChI:InChI=1/C14H19BO4/c1-13(2)14(3,4)19-15(18-13)11-8-6-7-10(9-11)12(16)17-5/h6-9H,1-5H3

Upstream product

• 1877-71-0 benzene 1,3-dicarboxylic acid monomethyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 52178-50-4 Methyl 3-formylbenzoate 
• 93-58-3 benzoic acid methyl ester 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 938071-03-5 bis[3-(methoxycarbonyl)phenyl]iodonium bromide 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 99769-19-4 [3-(methoxycarbonyl)phenyl]boronic acid 
• 618-89-3 methyl 3-bromobenzoate 
• 2905-65-9 methyl 3-chlorobenzoate 
• 1276637-19-4 C₆H₅SO₂O(C₆H₄COOCH₃) 
• 107658-28-6 methyl 3-(trifluoromethylsulfonyloxy)benzoate 
• 161912-35-2 methyl 3-((methylsulfonyl)oxy)benzoate 
• 19438-10-9 methyl 3-hydroxybenzoate 

Downstream Products

• 107558-26-9 methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate 
• 19617-68-6 methyl 4′-methoxy(1,1′-biphenyl)-3-carboxylate 
• 1751-97-9 biphenyl-3,3'-dicarboxylic acid dimethyl ester 
• 269409-73-6 3-carboxyphenylboronic acid pinacol ester 
• 455-68-5 methyl 3-fluorobenzoate 
• 1431773-20-4 methyl 3-(8-(6-(3-tert-butylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoate 
• 1431772-96-1 N-(2-(dimethylamino)ethyl)-3-(8-(6-(2-methylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzamide 
• 1431773-97-5 methyl 3-(8-(6-(3,3-dimethylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoate 
• 1431773-13-5 3-(8-(6-(3,3-dimethylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoic acid 
• 1431773-98-6 methyl 3-(8-(6-(2,5-dimethylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)-benzoate 
• 1431773-15-7 3-(8-(6-(2,5-dimethylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoic acid 
• 1431773-99-7 methyl 3-(8-(6-(4,4-dimethylpiperidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoate 
• 1431773-16-8 3-(8-(6-(4,4-dimethylpiperidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoic acid 
• 1431773-70-4 methyl 3-(6-amino-5-bromopyridazin-3-yl)benzoate 

Relevant articles and documents

IrIII-based Octahedral Metalloligands Derived Primitive Cubic Frameworks for Enhanced CO2/N2 Separation

We developed a metalloligand strategy to construct porous frameworks, viz. the combined use of IrIII-based octahedral metalloligands and the linear unit [Ni(cyclam)] easily afforded two isostructural complexes 1 and 2 with primitive cubic frameworks. Both complexes show good CO2/N2 separation property.

Synthesis and evaluation of tiaprofenic acid-derived UCHL5 deubiquitinase inhibitors

The ubiquitin–proteasome system (UPS) plays an important role in maintaining protein homeostasis by degrading intracellular proteins. In the proteasome, poly-ubiquitinated proteins are deubiquitinated by three deubiquitinases (DUBs) associated with 19S re

Controllable factors of supported IR complex catalysis for aromatic C?H borylation

We have developed a catalyst in which an Ir complex and organic functionalities are coimmobilized on the silica surface. The catalytic activity for aromatic C?H borylation was significantly affected by (i) the linker length of the Ir?bipyridine complex, (ii) the coimmobilized organic functionality, and (iii) the substituents on the aromatic substrate compounds. The fine-tuned supported catalyst showed higher activity than the homogeneous Ir?bipyridine complex when using a specific substrate such as benzonitrile. We elucidated this property by conducting solid-state NMR, FT-IR, XAFS, and in situ FT-IR analysis.