484-38-8

Basic information

• Product Name: isatic acid
• Synonyms: aminobenzoylformic acid;isatic acid;2-(2-Aminophenyl)glyoxylic acid;2-Aminobenzoylformic acid;Isatinic acid;2-(2-AMinophenyl)-2-oxoacetic acid;2-Amino-a-oxo-benzeneacetic acid
• CAS NO: 484-38-8
• Molecular Formula: C₈H₇NO₃
• Molecular Weight: 165.15
• Mol File: 484-38-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 344.4±34.0 °C(Predicted)
• Appearance: /
• Density: 1.401±0.06 g/cm3(Predicted)
• PKA: 2.06±0.54(Predicted)
• CAS DataBase Reference: isatic acid(CAS DataBase Reference)
• NIST Chemistry Reference: isatic acid(484-38-8)
• EPA Substance Registry System: isatic acid(484-38-8)

Safety Data

• Hazardous Substances Data: 484-38-8(Hazardous Substances Data)

Usage

General Description

Isatic acid, also known as 1,11-dioxo-1H,11H-pyrido[2,3-b][1,4]benzothiazine-1,11-dicarboxylic acid, is a compound with the molecular formula C13H6N2O6S. It is a yellow crystalline solid that is sparingly soluble in water and ethanol. Isatic acid is used as a building block in the synthesis of various pharmaceuticals and dyes. It has also been studied for its potential anti-inflammatory and antiviral properties. Isatic acid is a relatively rare compound, but its derivatives and analogs have been investigated for their potential pharmacological activities. Its chemical structure and properties make it an interesting target for further research and development in the field of medicinal chemistry.

Upstream product

• 91-56-5 indole-2,3-dione 
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• 85080-47-3 (2-benzoylamino-phenyl)-glyoxylic acid amide 
• 39755-95-8 5-methoxyisatine 
• 51731-17-0 trans-4-methoxy-3-buten-2-one 
• 476-34-6 isoindigo 
• 479-41-4 indirubin 
• 64784-13-0 indigo 
• 127280-19-7 (E)-3-<2-(Benzoylamino)phenyl>propenal 
• 574-17-4 1-acetyl-1H-indole-2,3-dione 
• 642-91-1 anthroxanic acid 
• 81964-71-8 N-(2-(2-oxo-2-(phenylamino)acetyl)phenyl)benzamide 
• 32375-61-4 2-(2-acetamidophenyl)-2-oxoacetic acid 

Downstream Products

• 5466-50-2 3-Nitro-cinchoninsaeure 
• 20389-09-7 2-(2-chlorophenyl)-quinoline-4-carboxylic acid 
• 128253-95-2 7-bromo-10H-indolo[3,2-b]quinoline-11-carboxylic acid 
• 98179-91-0 2,2-bis-(2-amino-phenyl)-2,2'-azino-di-acetic acid 
• 17392-16-4 (2-hydroxyphenyl)oxoacetic acid 
• 91-56-5 indole-2,3-dione 
• 117-57-7 3-hydroxy-2-methyl-4-quinolinecarboxylic acid 
• 485-89-2 oxycinchophen 
• 118-92-3 anthranilic acid 
• 486-74-8 4-quinolinic acid 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 1678-71-3 2-hydroxymandelic acid 

Relevant articles and documents

Kinetics and mechanism of isatin ring opening in aqueous binary mixtures of methanol and acetonitrile cosolvents

Solvent effects on the kinetics of hydrolysis of isatin by sodium hydroxide have been investigated within the temperature range (30-55 °C) in methanol-water and acetonitrile-water media of varying solvent compositions up to 70% (v/v) of the organic solven

Kinetic spectrophotometric methods for the determination of isatin

Simple, rapid and sensitive kinetic spectrophotometric methods are described for the analysis of isatin in pure form and in mixture. The procedures were based on the kinetic investigations and studies were done upon the oxidation of isatin with potassium

Synthesis of 6,7-dihydrodibenzo[b,j]phenanthroline derivatives by pfitzinger condensation of isatin and cyclic diketones

All two kinds of 6,7-dihydrodibenzo[b,j]phenanthroline derivatives were synthesized by Pfitzinger condensation of isatins with 1,3-cyclohexanedione and 1,4-cyclohexanedione respectively. Structures of the derivatives were confirmed by NMR and other spectr